Marchiafava-Bignami disease

Marchiafava-Bignami disease
Marchiafava-Bignami disease
Classification and external resources
ICD-10 G37.1
ICD-9 341.8
DiseasesDB 31494
eMedicine neuro/204
MeSH D054319

Marchiafava-Bignami disease is a progressive neurological disease characterized by corpus callosum demyelination and necrosis and subsequent atrophy.

Contents

Eponym

It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.[1][2] In this patient, Marchiafava and Bignami noticed that the middle two-thirds of the corpus callosum were necrotic.

Causes

It is classically associated with chronic alcoholics and sometimes nutritional deficiencies.

See also

Central pontine myelinolysis

References

  1. ^ synd/2922 at Who Named It?
  2. ^ E. Marchiafava, A. Bignami. Sopra un' alterazione del corpo calloso osservata da sogetti alcoolisti. Rivista di patologia nervosa e mentale, 1903, 8 (12): 544-549.

External links


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Look at other dictionaries:

  • Marchiafava-Bignami disease — Mar·chi·a·fa·va Bi·gna·mi disease (mahr″ke ə fahґvah be nyahґme) [Ettore Marchiafava, Italian pathologist, 1847–1935; Amico Bignami, Italian pathologist, 1862–1929] see under disease …   Medical dictionary

  • Marchiafava-Bignami disease — progressive degeneration of the corpus callosum characterized by progressive intellectual deterioration, emotional disturbances, confusion, hallucinations, tremor, rigidity, and convulsions. It is a very rare disorder affecting chiefly middle… …   Medical dictionary

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