- Cinchocaine
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Cinchocaine 
Systematic (IUPAC) name 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide Clinical data AHFS/Drugs.com International Drug Names Pregnancy cat. ? Legal status ? Routes topical, intravenous (equine euthanasia) Identifiers CAS number 85-79-0 ATC code C05AD04 D04AB02 N01BB06 S01HA06 PubChem CID 3025 DrugBank APRD00915 ChemSpider 2917 
UNII L6JW2TJG99 KEGG D00733 ChEBI CHEBI:247956 ChEMBL CHEMBL1086 Chemical data Formula C20H29N3O2 Mol. mass 343.463 g/mol SMILES eMolecules & PubChem - InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)
Key:PUFQVTATUTYEAL-UHFFFAOYSA-N
(what is this?) (verify)Cinchocaine (or Dibucaine) is an amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine [1].
Dibucaine is insoluble in alkaline aquatic environments.
It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.
See also
External links
- Abdel-Ghani N, Youssef A, Awady M (2005). "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry.". Farmaco 60 (5): 419–24. doi:10.1016/j.farmac.2005.03.001. PMID 15910814.
- Souto-Padron T, Lima AP, de Oliveira Ribeiro R. (2006). "Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi.". Parasitol Res 99 (4): 317. doi:10.1007/s00436-006-0192-1. PMID 16612626.
- Nounou M, El-Khordagui L, Khalafallah N (2005). "Effect of various formulation variables on the encapsulation and stability of dibucaine base in multilamellar vesicles.". Acta Pol Pharm 62 (5): 369–79. PMID 16459486.
- Aroti,A.;Leontidis, E. (2001). Journal of Chemical Education 76: 786–788.
Vasoprotectives (C05) Antihemorrhoidals for topical use corticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide)
local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine)
other (Tribenoside)Antivaricose therapy heparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate)
sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol)
other (Calcium dobesilate)Capillary stabilising agents bioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside, Etamsylate)Antipruritics (D04) Antihistamines for topical use Anesthetics for topical use Anesthetics: Local anesthetics - primarily sodium channel blockers (N01B) Esters Esters of aminobenzoic acidAmylocaine • Benzocaine • Butacaine • Butamben • Chloroprocaine • Dimethocaine • Meprylcaine • Metabutoxycaine • Orthocaine • Propoxycaine • Procaine (Novocaine) • Proxymetacaine • Risocaine • TetracaineEsters of benzoic acidAmides Articaine • Bupivacaine # /Levobupivacaine/Ropivacaine • Carticaine • Cinchocaine • Etidocaine • Lidocaine # • Mepivacaine • Prilocaine • TrimecaineCombinations 
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. This dermatologic drug article is a stub. You can help Wikipedia by expanding it. This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. - InChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)
