- Carboxy-lyases
-
Carboxy-lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds. These enzymes catalyze the decarboxylation of amino acids, beta-keto acids and alpha-keto acids[1].
Contents
Classification and nomenclature
Carboxy-lyases are categorized under EC number 4.1.1. [2] Usually, they are named after the substrate whose decarboxylation they catalyze, for example Pyruvate decarboxylase catalyzes the decarboxylation of Pyruvate
Examples
- Aromatic-L-amino-acid decarboxylase
- Glutamate decarboxylase
- Histidine decarboxylase
- Ornithine decarboxylase
- Phosphoenolpyruvate carboxylase
- Pyruvate decarboxylase
- RuBisCO – the only carboxylase that leads to a net fixation of carbon dioxide
- Uridine monophosphate synthetase
- Uroporphyrinogen III decarboxylase
See also
External links
References
Carbon-carbon lyases (EC 4.1) 4.1.1: Carboxy-lyases Pyruvate decarboxylase · Oxaloacetate decarboxylase · Acetoacetate decarboxylase · Malonyl-CoA decarboxylase · Glutamate decarboxylase · Ornithine decarboxylase · Lysine decarboxylase · Phosphoribosylaminoimidazole carboxylase · Histidine decarboxylase · Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase · Aromatic L-amino acid decarboxylase · Phosphoenolpyruvate carboxylase · Pyrophosphomevalonate decarboxylase · Uroporphyrinogen III decarboxylase · RuBisCO · Phosphoenolpyruvate carboxykinase · Adenosylmethionine decarboxylase4.1.2: Aldehyde-lyases 4.1.3: Oxo-acid-lyases 4.1.99: Other B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6 Categories:- EC 4.1 stubs
- EC 4.1.1
Wikimedia Foundation. 2010.
