List of EC numbers (EC 3)

List of EC numbers (EC 3)

This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

EC 3.1: Acting on Ester Bonds

EC 3.1.1: Carboxylic Ester Hydrolases

*: carboxylesterase
*: arylesterase
*: triacylglycerol lipase
*: phospholipase A2
*: lysophospholipase
*: acetylesterase
*: acetylcholinesterase
*: cholinesterase
*: deleted
*: tropinesterase
*: pectinesterase
*: deleted
*: sterol esterase
*: chlorophyllase
*: L-arabinonolactonase
*: deleted, mixture of EC 5.3.3.4 and EC 3.1.1.24
*: gluconolactonase
*: deleted, included in EC 3.1.1.17
*: uronolactonase
*: tannase
*: retinyl-palmitate esterase
*: hydroxybutyrate-dimer hydrolase
*: acylglycerol lipase
*: 3-oxoadipate enol-lactonase
*: 1,4-lactonase
*: galactolipase
*: 4-pyridoxolactonase
*: acylcarnitine hydrolase
*: aminoacyl-tRNA hydrolase
*: D-arabinonolactonase
*: 6-phosphogluconolactonase
*: phospholipase A1
*: 6-acetylglucose deacetylase
*: lipoprotein lipase
*: dihydrocoumarin hydrolase
*: limonin-D-ring-lactonase
*: steroid-lactonase
*: triacetate-lactonase
*: actinomycin lactonase
*: orsellinate-depside hydrolase
*: cephalosporin-C deacetylase
*: chlorogenate hydrolase
*: a-amino-acid esterase
*: 4-methyloxaloacetate esterase
*: carboxymethylenebutenolidase
*: deoxylimonate A-ring-lactonase
*: 1-alkyl-2-acetylglycerophosphocholine esterase
*: fusarinine-C ornithinesterase
*: sinapine esterase
*: wax-ester hydrolase
*: phorbol-diester hydrolase
*: phosphatidylinositol deacylase
*: sialate O-acetylesterase
*: acetoxybutynylbithiophene deacetylase
*: acetylsalicylate deacetylase
*: methylumbelliferyl-acetate deacetylase
*: 2-pyrone-4,6-dicarboxylate lactonase
*: N-acetylgalactosaminoglycan deacetylase
*: juvenile-hormone esterase
*: bis(2-ethylhexyl)phthalate esterase
*: protein-glutamate methylesterase
*: now EC 3.5.1.47
*: 11-cis-retinyl-palmitate hydrolase
*: all-trans-retinyl-palmitate hydrolase
*: L-rhamnono-1,4-lactonase
*: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
*: fatty-acyl-ethyl-ester synthase
*: xylono-1,4-lactonase
*: now EC 3.5.1.89
*: cetraxate benzylesterase
*: acetylalkylglycerol acetylhydrolase
*: acetylxylan esterase
*: feruloyl esterase
*: cutinase
*: poly(3-hydroxybutyrate) depolymerase
*: poly(3-hydroxyoctanoate) depolymerase
*: acyloxyacyl hydrolase
*: polyneuridine-aldehyde esterase
*: hormone-sensitive lipase

EC 3.1.2: Thioester Hydrolases

*: acetyl-CoA hydrolase
*: palmitoyl-CoA hydrolase
*: succinyl-CoA hydrolase
*: 3-hydroxyisobutyryl-CoA hydrolase
*: hydroxymethylglutaryl-CoA hydrolase
*: hydroxyacylglutathione hydrolase
*: glutathione thiolesterase
*: deleted, included in EC 3.1.2.6
*: deleted
*: formyl-CoA hydrolase
*: acetoacetyl-CoA hydrolase
*: S-formylglutathione hydrolase
*: S-succinylglutathione hydrolase
*: oleoyl-(acyl-carrier-protein) hydrolase
*: ubiquitin thiolesterase
*: citrate lyase deacetylase
*: (S)-methylmalonyl-CoA hydrolase
*: ADP-dependent short-chain-acyl-CoA hydrolase
*: ADP-dependent medium-chain-acyl-CoA hydrolase
*: acyl-CoA hydrolase
*: dodecanoyl-(acyl-carrier protein) hydrolase
*: palmitoyl(protein) hydrolase
*: 4-hydroxybenzoyl-CoA thioesterase
*: transferred entry now EC 3.13.1.3
*: phenylacetyl-CoA hydrolase
*: bile-acid-CoA hydrolase
*: choloyl-CoA hydrolase

EC 3.1.3: Phosphoric Monoester Hydrolases

*: alkaline phosphatase
*: acid phosphatase
*: phosphoserine phosphatase
*: phosphatidate phosphatase
*: 5'-nucleotidase
*: 3'-nucleotidase
*: 3'(2'),5'-bisphosphate nucleotidase
*: 3-phytase
*: glucose-6-phosphatase
*: glucose-1-phosphatase
*: fructose-bisphosphatase
*: trehalose-phosphatase
*: bisphosphoglycerate phosphatase
*: methylphosphothioglycerate phosphatase
*: histidinol-phosphatase
*: phosphoprotein phosphatase
*: (phosphorylase) phosphatase
*: phosphoglycolate phosphatase
*: glycerol-2-phosphatase
*: phosphoglycerate phosphatase
*: glycerol-1-phosphatase
*: mannitol-1-phosphatase
*: sugar-phosphatase
*: sucrose-phosphatase
*: inositol-phosphate phosphatase
*: 4-phytase
*: phosphatidylglycerophosphatase
*: ADP-phosphoglycerate phosphatase
*: N-acylneuraminate-9-phosphatase
*: deleted, included in EC 3.1.3.31
*: nucleotidase
*: polynucleotide 3'-phosphatase
*: polynucleotide 5'-phosphatase
*: deoxynucleotide 3'-phosphatase
*: thymidylate 5'-phosphatase
*: phosphoinositide 5-phosphatase
*: sedoheptulose-bisphosphatase
*: 3-phosphoglycerate phosphatase
*: streptomycin-6-phosphatase
*: guanidinodeoxy-scyllo-inositol-4-phosphatase
*: 4-nitrophenylphosphatase
*: (glycogen-synthase-D) phosphatase
*: (pyruvate dehydrogenase (acetyl-transferring))-phosphatase
*: (acetyl-CoA carboxylase)-phosphatase
*: 3-deoxy-manno-octulosonate-8-phosphatase
*: fructose-2,6-bisphosphate 2-phosphatase
*: (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase
*: protein-tyrosine-phosphatase
*: (pyruvate kinase)-phosphatase
*: sorbitol-6-phosphatase
*: dolichyl-phosphatase
*: (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase
*: (myosin-light-chain) phosphatase
*: fructose-2,6-bisphosphate 6-phosphatase
*: caldesmon-phosphatase
*: inositol-polyphosphate 5-phosphatase
*: inositol-1,4-bisphosphate 1-phosphatase
*: sugar-terminal-phosphatase
*: alkylacetylglycerophosphatase
*: phosphoenolpyruvate phosphatase
*: deleted
*: multiple inositol-polyphosphate phosphatase
*: 2-carboxy-D-arabinitol-1-phosphatase
*: phosphatidylinositol-3-phosphatase
*: now with EC 3.1.3.64
*: phosphatidylinositol-3,4-bisphosphate 4-phosphatase
*: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
*: 2-deoxyglucose-6-phosphatase
*: glucosylglycerol 3-phosphatase
*: mannosyl-3-phosphoglycerate phosphatase
*: 2-phosphosulfolactate phosphatase
*: 5-phytase
*: a-ribazole phosphatase
*: pyridoxal phosphatase
*: phosphoethanolamine/phosphocholine phosphatase

EC 3.1.4: Phosphoric Diester Hydrolases

*: phosphodiesterase I
*: glycerophosphocholine phosphodiesterase
*: lecithinase C
*: phospholipase D
*: now EC 3.1.21.1
*: now EC 3.1.22.1
*: now EC 3.1.31.1
*: now EC 3.1.27.3
*: now EC 3.1.30.2
*: now EC 4.6.1.13
*: phosphoinositide phospholipase C
*: sphingomyelin phosphodiesterase
*: serine-ethanolaminephosphate phosphodiesterase
*: (acyl-carrier-protein) phosphodiesterase
*: adenylyl-(glutamate—ammonia ligase) hydrolase
*: 2',3'-cyclic-nucleotide 2'-phosphodiesterase
*: 3',5'-cyclic-nucleotide phosphodiesterase
*: now EC 3.1.16.1
*: now EC 3.1.13.3
*: now EC 3.1.13.1
*: now EC 3.1.30.1
*: now EC 3.1.27.5
*: now EC 3.1.27.1
*: deleted
*: now EC 3.1.11.1
*: deleted
*: now EC 3.1.11.2
*: now EC 3.1.11.3
*: deleted
*: now EC 3.1.21.2
*: now EC 3.1.11.4
*: deleted
*: deleted
*: deleted
*: 3',5'-cyclic-GMP phosphodiesterase
*: now with EC 3.1.4.43
*: 2',3'-cyclic-nucleotide 3'-phosphodiesterase
*: glycerophosphocholine cholinephosphodiesterase
*: alkylglycerophosphoethanolamine phosphodiesterase
*: CMP-N-acylneuraminate phosphodiesterase
*: sphingomyelin phosphodiesterase D
*: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
*: glycerophosphoinositol inositolphosphodiesterase
*: glycerophosphoinositol glycerophosphodiesterase
*: N-acetylglucosamine-1-phosphodiester a-N-acetylglucosaminidase
*: glycerophosphodiester phosphodiesterase
*: now EC 4.6.1.14
*: dolichylphosphate-glucose phosphodiesterase
*: dolichylphosphate-mannose phosphodiesterase
*: glycosylphosphatidylinositol phospholipase D
*: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase

EC 3.1.5: Triphosphoric Monoester Hydrolases

*: dGTPase

EC 3.1.6: Sulfuric Ester Hydrolases

*: arylsulfatase
*: steryl-sulfatase
*: glycosulfatase
*: N-acetylgalactosamine-6-sulfatase
*: deleted
*: choline-sulfatase
*: cellulose-polysulfatase
*: cerebroside-sulfatase
*: chondro-4-sulfatase
*: chondro-6-sulfatase
*: disulfoglucosamine-6-sulfatase
*: N-acetylgalactosamine-4-sulfatase
*: iduronate-2-sulfatase
*: N-acetylglucosamine-6-sulfatase
*: N-sulfoglucosamine-3-sulfatase
*: monomethyl-sulfatase
*: D-lactate-2-sulfatase
*: glucuronate-2-sulfatase

EC 3.1.7: Diphosphoric Monoester Hydrolases

*: prenyl-diphosphatase
*: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
*: monoterpenyl-diphosphatase

EC 3.1.8: Phosphoric Triester Hydrolases

*: aryldialkylphosphatase
*: diisopropyl-fluorophosphatase

EC 3.1.11: Exodeoxyribonucleases Producing 5'-Phosphomonoesters

*: exodeoxyribonuclease I
*: exodeoxyribonuclease III
*: exodeoxyribonuclease (lambda-induced)
*: exodeoxyribonuclease (phage SP3-induced)
*: exodeoxyribonuclease V
*: exodeoxyribonuclease VII

EC 3.1.13: Exoribonucleases Producing 5'-Phosphomonoesters

*: exoribonuclease II
*: exoribonuclease H
*: oligonucleotidase
*: poly(A)-specific ribonuclease

EC 3.1.14: Exoribonucleases Producing 3'-Phosphomonoesters

*: yeast ribonuclease

EC 3.1.15: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

*: venom exonuclease

EC 3.1.16: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

*: spleen exonuclease

EC 3.1.21: Endodeoxyribonucleases Producing 5'-Phosphomonoesters

*: deoxyribonuclease I
*: deoxyribonuclease IV (phage-T4-induced)
*: type I site-specific deoxyribonuclease
*: type II site-specific deoxyribonuclease
*: type III site-specific deoxyribonuclease
*: CC-preferring endodeoxyribonuclease
*: deoxyribonuclease V

EC 3.1.22: Endodeoxyribonucleases Producing 3'-Phosphomonoesters

*: deoxyribonuclease II
*: Aspergillus deoxyribonuclease K1
*: now EC 3.1.21.7
*: crossover junction endodeoxyribonuclease
*: deoxyribonuclease X

EC 3.1.23: and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5

EC 3.1.25: Site-Specific Endodeoxyribonucleases Specific for Altered Bases

*: deoxyribonuclease (pyrimidine dimer)
*: now EC 4.2.99.18

EC 3.1.26: Endoribonucleases Producing 5'-Phosphomonoesters

*: Physarum polycephalum ribonuclease
*: ribonuclease alpha
*: ribonuclease III
*: calf thymus ribonuclease H
*: ribonuclease P
*: ribonuclease IV
*: ribonuclease P4
*: ribonuclease M5
*: ribonuclease (poly-(U)-specific)
*: ribonuclease IX
*: tRNase Z

EC 3.1.27: Endoribonucleases Producing 3'-Phosphomonoesters

*: ribonuclease T2
*: Bacillus subtilis ribonuclease
*: ribonuclease T1
*: ribonuclease U2
*: pancreatic ribonuclease
*: Enterobacter ribonuclease
*: ribonuclease F
*: ribonuclease V
*: tRNA-intron endonuclease
*: rRNA endonuclease

EC 3.1.30: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

*: Aspergillus nuclease S1
*: Serratia marcescens nuclease

EC 3.1.31: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

*: micrococcal nuclease

EC 3.2: Glycosylases

EC 3.2.1: Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds

*: α-amylase
*: β-amylase
*: glucan 1,4-a-glucosidase
*: cellulase
*: deleted
*: endo-1,3(4)-b-glucanase
*: inulinase
*: endo-1,4-β-xylanase
*: deleted
*: oligo-1,6-glucosidase
*: dextranase
*: deleted, included in EC 3.2.1.54
*: deleted, included in EC 3.2.1.54
*: chitinase
*: polygalacturonase
*: deleted
*: lysozyme
*: exo-a-sialidase
*: deleted
*: a-glucosidase
*: b-glucosidase
*: α-galactosidase
*: b-galactosidase
*: a-mannosidase
*: b-mannosidase
*: b-fructofuranosidase
*: deleted
*: α,α-trehalase
*: deleted, included in EC 3.2.1.52
*: deleted, included in EC 3.2.1.52
*: β-glucuronidase
*: xylan endo-1,3-b-xylosidase
*: amylo-1,6-glucosidase
*: deleted, included in EC 3.2.1.35
*: hyaluronoglucosaminidase
*: hyaluronoglucuronidase
*: xylan 1,4-b-xylosidase
*: b-D-fucosidase
*: glucan endo-1,3-b-D-glucosidase
*: a-L-rhamnosidase
*: pullulanase
*: GDP-glucosidase
*: b-L-rhamnosidase
*: fucoidanase
*: glucosylceramidase
*: galactosylceramidase
*: galactosylgalactosylglucosylceramidase
*: sucrose a-glucosidase
*: a-N-acetylgalactosaminidase
*: α-N-acetylglucosaminidase
*: a-L-fucosidase
*: b-L-N-acetylhexosaminidase
*: b-N-acetylgalactosaminidase
*: cyclomaltodextrinase
*: a-N-arabinofuranosidase
*: glucuronosyl-disulfoglucosamine glucuronidase
*: isopullulanase
*: glucan 1,3-b-glucosidase
*: glucan endo-1,3-a-glucosidase
*: glucan 1,4-a-maltotetraohydrolase
*: mycodextranase
*: glycosylceramidase
*: 1,2-a-L-fucosidase
*: 2,6-b-fructan 6-levanbiohydrolase
*: levanase
*: quercitrinase
*: galacturan 1,4-a-galacturonidase
*: isoamylase
*: deleted, included in EC 3.2.1.41
*: glucan 1,6-a-glucosidase
*: glucan endo-1,2-b-glucosidase
*: xylan 1,3-b-xylosidase
*: licheninase
*: glucan 1,4-b-glucosidase
*: glucan endo-1,6-b-glucosidase
*: L-iduronidase
*: mannan 1,2-(1,3)-a-mannosidase
*: mannan endo-1,4-b-mannosidase
*: deleted, included in EC 3.2.1.55
*: fructan b-fructosidase
*: agarase
*: exo-poly-a-galacturonosidase
*: k-carrageenase
*: glucan 1,3-a-glucosidase
*: 6-phospho-b-galactosidase
*: 6-phospho-b-glucosidase
*: capsular-polysaccharide endo-1,3-a-galactosidase
*: b-L-arabinosidase
*: arabinogalactan endo-1,4-b-galactosidase
*: Deleted, not sufficiently characterised.
*: cellulose 1,4-b-cellobiosidase
*: peptidoglycan b-N-acetylmuramidase
*: a,a-phosphotrehalase
*: glucan 1,6-a-isomaltosidase
*: dextran 1,6-a-isomaltotriosidase
*: mannosyl-glycoprotein endo-b-N-acetylglucosaminidase
*: glycopeptide a-N-acetylgalactosaminidase
*: glucan 1,4-a-maltohexaosidase
*: arabinan endo-1,5-a-L-arabinosidase
*: mannan 1,4-mannobiosidase
*: mannan endo-1,6-a-mannosidase
*: blood-group-substance endo-1,4-b-galactosidase
*: keratan-sulfate endo-1,4-b-galactosidase
*: steryl-b-glucosidase
*: strictosidine b-glucosidase
*: mannosyl-oligosaccharide glucosidase
*: protein-glucosylgalactosylhydroxylysine glucosidase
*: lactase
*: endogalactosaminidase
*: mucinaminylserine mucinaminidase
*: 1,3-a-L-fucosidase
*: 2-deoxyglucosidase
*: mannosyl-oligosaccharide 1,2-a-mannosidase
*: mannosyl-oligosaccharide 1,3-1,6-a-mannosidase
*: branched-dextran exo-1,2-a-glucosidase
*: glucan 1,4-a-maltotriohydrolase
*: amygdalin b-glucosidase
*: prunasin b-glucosidase
*: vicianin b-glucosidase
*: oligoxyloglucan b-glycosidase
*: polymannuronate hydrolase
*: maltose-6'-phosphate glucosidase
*: endoglycosylceramidase
*: 3-deoxy-2-octulosonidase
*: raucaffricine b-glucosidase
*: coniferin b-glucosidase
*: 1,6-a-L-fucosidase
*: glycyrrhizinate b-glucuronidase
*: endo-a-sialidase
*: glycoprotein endo-a-1,2-mannosidase
*: xylan a-1,2-glucuronosidase
*: chitosanase
*: glucan 1,4-a-maltohydrolase
*: difructose-anhydride synthase
*: neopullulanase
*: glucuronoarabinoxylan endo-1,4-b-xylanase
*: mannan exo-1,2-1,6-a-mannosidase
*: now EC 4.2.2.15
*: a-glucuronidase
*: lacto-N-biosidase
*: 4-a-D-((1(arrow to right)4)-a-D-glucano}trehalose trehalohydrolase
*: limit dextrinase
*: poly(ADP-ribose) glycohydrolase
*: 3-deoxyoctulosonase
*: galactan 1,3-b-galactosidase
*: b-galactofuranosidase
*: thioglucosidase
*: now EC 4.4.1.21
*: b-primeverosidase
*: oligoxyloglucan reducing-end-specific cellobiohydrolase
*: xyloglucan-specific endo-b-1,4-glucanase
*: mannosylglycoprotein endo-b-mannosidase
*: fructan b-(2,1)-fructosidase
*: fructan b-(2,6)-fructosidase
*: oligosaccharide reducing-end xylanase

EC 3.2.2: Hydrolysing N-Glycosyl Compounds

*: purine nucleosidase
*: inosine nucleosidase
*: uridine nucleosidase
*: AMP nucleosidase
*: NAD+ nucleosidase
*: NAD(P)+ nucleosidase
*: adenosine nucleosidase
*: ribosylpyrimidine nucleosidase
*: adenosylhomocysteine nucleosidase
*: pyrimidine-5'-nucleotide nucleosidase
*: b-aspartyl-N-acetylglucosaminidase
*: inosinate nucleosidase
*: 1-methyladenosine nucleosidase
*: NMN nucleosidase
*: DNA-deoxyinosine glycosylase
*: methylthioadenosine nucleosidase
*: deoxyribodipyrimidine endonucleosidase
*: deleted, included in EC 3.5.1.52
*: ADP-ribosylarginine hydrolase
*: DNA-3-methyladenine glycosylase I
*: DNA-3-methyladenine glycosylase II
*: rRNA N-glycosylase
*: DNA-formamidopyrimidine glycosylase
*: ADP-ribosyl-(dinitrogen reductase) hydrolase

EC 3.2.3: Hydrolysing S-Glycosyl Compounds

*: now EC 3.2.1.147

EC 3.3: Acting on Ether Bonds

EC 3.3.1: Thioether and trialkylsulfonium hydrolases

*: adenosylhomocysteinase
*: adenosylmethionine hydrolase
*: now EC 3.2.1.148

EC 3.3.2: Ether Hydrolases

*: isochorismatase
*: alkenylglycerophosphocholine hydrolase
*: epoxide hydrolase
*: trans-epoxysuccinate hydrolase
*: alkenylglycerophosphoethanolamine hydrolase
*: leukotriene-A4 hydrolase
*: hepoxilin-epoxide hydrolase
*: limonene-1,2-epoxide hydrolase

EC 3.4: act on peptide bonds - Peptidase

EC 3.4.1 α-amino acyl peptide hydrolases (discontinued)

*: leucine aminopeptidase now EC number|3.4.11.1
*: alanine aminopeptidase now EC number|3.4.11.2
*: aminotripeptidase now EC number|3.4.11.4
*: proline iminopeptidase now EC number|3.4.11.5

EC 3.4.2 Peptidyl amino acid hydrolases (discontinued)

*: carboxypeptidase A now EC number|3.4.17.1
*: carboxypeptidase B now EC number|3.4.17.2
*: yeast carboxypeptidase now EC number|3.4.17.4

EC 3.4.3 Dipeptide Hydrolases (discontinued)

*: glycyl-glycine dipeptidase now EC number|3.4.13.18
*: glycyl-leucine dipeptidase now EC number|3.4.13.18
*: aminoacyl-histidine dipeptidase, carnosinase now EC number|3.4.13.3
*: aminoacyl-methylhistidine dipeptidase, anserinase now EC number|3.4.13.5
*: cysteinyl-glycine dipeptidase now EC number|3.4.13.6
*: iminodipeptidase now EC number|3.4.13.8
*: imidodipeptidase, prolidase now EC number|3.4.13.9

EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued)

*: pepsin now EC number|3.4.23.1
*: pepsin B now EC number|3.4.23.2
*: rennin now EC number|3.4.23.4
*: trypsin now EC number|3.4.21.4
*: chymotrypsin now EC number|3.4.21.1
*: chymotrypsin B now EC number|3.4.21.1
*: pancreatopeptidase E now EC number|3.4.21.36 and EC number|3.4.21.37
*: enteropeptidase now EC number|3.4.21.9
*: cathepsin C now EC number|3.4.14.1
*: papain now EC number|3.4.22.2
*: chymopapain now EC number|3.4.22.6
*: ficin now EC number|3.4.22.3
*: thrombin now EC number|3.4.21.5
*: plasmin now EC number|3.4.21.7
*: renin now EC number|3.4.23.15
*: subtilopeptidase A now EC number|3.4.21.62 to EC number|3.4.21.67
*: aspergillopeptidase A now EC number|3.4.23.20 to EC number| 3.4.23.30
*: streptococcus peptidase A now EC number|3.4.22.10
*: clostridiopeptidase A now EC number|3.4.24.3
*: clostridiopeptidase B now EC number|3.4.22.8
*: kallikrein now EC number|3.4.21.34
*: recommended Name never specified now EC number|3.4.23.3
*: recommended Name never specified now EC number|3.4.23.5
*: recommended Name never specified now EC number|3.4.22.32 and EC number|3.4.22.33
*: keratinase deleted

EC 3.4.11 Aminopeptidases

*: leucyl aminopeptidase
*: membrane alanyl aminopeptidase
*: cystinyl aminopeptidase
*: tripeptide aminopeptidase
*: prolyl aminopeptidase
*: aminopeptidase B
*: glutamyl aminopeptidase
*: pyroglutamyl aminopeptidase
*: X-Pro aminopeptidase
*: bacterial leucyl aminopeptidase
*: aminopeptidase
*: thermophilic aminopeptidase
*: Clostridial aminopeptidase
*: cytosol alanyl aminopeptidase
*: aminopeptidase Y
*: X-Trp aminopeptidase
*: tryptophanyl aminopeptidase
*: methionyl aminopeptidase
*: D-stereospecific aminopeptidase
*: aminopeptidase Ey
*: aspartyl aminopeptidase
*: aminopeptidase I
*: PepB aminopeptidase

EC 3.4.13 Dipeptidases

*: glycyl-glycine dipeptidase
*: glycyl-leucine dipeptidase
*: X-His dipeptidase
*: X-Arg dipeptidase
*: X-methyl-His dipeptidase
*: Cys-Gly dipeptidase
*: Glu-Glu dipeptidase
*: Pro-X dipeptidase
*: X-Pro dipeptidase
*: beta-aspartyldipeptidase
*: dipeptidase
*: Met-X dipeptidase
*: homocarnosinase
*: gamma-glutamyldipeptidase
*: N2-beta-alanylarginine dipeptidase
*: aspartylphenylalanine dipeptidase
*: non-stereospecific dipeptidase
*: cytosol nonspecific dipeptidase
*: membrane dipeptidase
*: beta-Ala-His dipeptidase
*: dipeptidase E

EC 3.4.14 Dipeptidyl peptidases and tripeptidyl peptidases

*: dipeptidyl-peptidase I
*: dipeptidyl-peptidase II
*: acylamino-acid-releasing enzyme
*: dipeptidyl-peptidase III
*: dipeptidyl-peptidase IV
*: dipeptidyl-dipeptidase
*: tetralysine endopeptidase
*: tripeptidyl peptidase
*: tripeptidyl-peptidase I
*: tripeptidyl-peptidase II
*: Xaa-Pro dipeptidyl-peptidase

EC 3.4.15 Peptidyl dipeptidases

*: peptidyl-dipeptidase A
*: pepdidyl carboxyamidase
*: dipeptidyl carboxypeptidase
*: Peptidyl-dipeptidase B
*: Peptidyl-dipeptidase Dcp

EC 3.4.16 Serine type carboxypeptidases

*: serine carboxypeptidase
*: lysosomal Pro-X carboxypeptidase
*: tyrosine carboxypeptidase
*: serine-type D-Ala-D-Ala carboxypeptidase
*: carboxypeptidase C
*: carboxypeptidase D

EC 3.4.17 Metallocarboxypeptidases

*: carboxypeptidase A
*: carboxypeptidase B
*: lysine carboxypeptidase
*: Gly-X carboxypeptidase
*: aspartate carboxypeptidase
*: alanine carboxypeptidase
*: acylmuramoyl-alanine carboxypeptidase
*: muramoylpentapeptide carboxypeptidase
*: carboxypeptidase S
*: carboxypeptidase E
*: glutamate carboxypeptidase
*: carboxypeptidase M
*: Muramoyltetrapeptide carboxypeptidase
*: Zinc D-Ala-D-Ala carboxypeptidase
*: carboxypeptidase A2
*: Membrane Pro-X carboxypeptidase
*: tubulinyl-Tyr carboxypeptidase
*: carboxypeptidase T
*: Carboxypeptidase Taq
*: Carboxypeptidase U
*: Glutamate carboxypeptidase II
*: Metallocarboxypeptidase D

EC 3.4.18 Cysteine type carboxypeptidases

*: cathepsin X

EC 3.4.19 Omega peptidases

*: acylaminoacyl-peptidase
*: peptidyl-glycinamidase
*: pyroglutamyl-peptidase I
*: N-acetylmethionylpeptide peptidase
*: beta-aspartyl-peptidase
*: pyroglutamyl-peptidase II
*: N-Formylmethionyl-peptidase
*: recommended Name never specified
*: gamma-glutamyl hydrolase
*: acylmuramoyl-Ala peptidase
*: gamma-D-Glutamyl-meso-diaminopimelate peptidase
*: ubiquitinyl hydrolase 1

EC 3.4.21: Serine proteases

*: chymotrypsin
*: chymotrypsin C
*: metridin
*: trypsin
*: thrombin
*: coagulation factor Xa
*: plasmin
*: kallikrein
*: enteropeptidase
*: acrosin
*: elastase
*: alpha-lytic endopeptidase
*: phaseolus proteinase
*: microbial serine proteases
*: Aspergillus alkaline proteinase
*: Alternaria serine proteinase
*: Arthrobacter serine proteinase
*: Tenebrio alpha-proteinase
*: glutamyl endopeptidase
*: cathepsin G
*: coagulation factor VIIa
*: coagulation factor IXa
*: Vipera russelli proteinase
*: red cell neutral endopeptidase
*: cucumisin
*: prolyl oligopeptidase
*: coagulation factor XIa
*: Agkistrodon serine proteinase
*: Bothrops atrox serine proteinase
*: Crotalus adamanteus serine proteinase
*: urokinase
*: brachyurin
*: Entomophthora collagenolytic proteinase
*: plasma kallikrein
*: renal tissue kallikrein
*: pancreatic elastase
*: leukocyte elastase
*: coagulation factor XIIa
*: chymase
*: submandibular proteinase A
*: complement subcomponent C1r
*: complement subcomponent C1s
*: classical-complement-pathway C3/C5 convertase
*: complement component C5 convertase
*: complement factor I
*: complement factor D
*: alternative-complement-pathway C3/C5 convertase
*: cerevisin
*: hypodermin C
*: lysyl endopeptidase
*: leukocyte-membrane neutral endopeptidase
*: cathepsin R
*: Endopeptidase La
*: gamma-Renin
*: Venombin AB
*: euphorbain
*: Leucyl endopeptidase
*: prohormone serine proteinase
*: Tryptase
*: Scutelarin
*: Kexin
*: Subtilisin
*: Oryzin
*: Endopeptidase K
*: Thermomycolin
*: Thermitase
*: Endopeptidase So
*: t-Plasminogen activator
*: Protein C (activated)
*: Pancreatic endopeptidase E
*: Pancreatic elastase II
*: IgA-specific serine endopeptidase
*: u-Plasminogen activator
*: Venombin A
*: Furin
*: Myeloblastin
*: semenogelase
*: Granzyme A
*: Granzyme B
*: Streptogrisin A
*: Streptogrisin B
*: Glutamyl endopeptidase II
*: Oligopeptidase B
*: Limulus clotting factor C
*: Limulus clotting factor B
*: Limulus clotting enzyme
*: Omptin
*: Repressor LexA
*: Signal peptidase I
*: Togavirin
*: Flavivirin
*: Endopeptidase Clp
*: Proprotein convertase 1
*: Proprotein convertase 2
*: Snake venom factor V activator
*: Lactocepin
*: assemblin
*: hepacivirin
*: spermosin
*: pseudomonalisin
*: xanthomonalisin
*: C-terminal processing peptidase
*: physarolisin
*: mannan-binding lectin-associated serine protease-2
*: rhomboid protease

EC 3.4.22 Cysteine proteases

*: cathepsin B
*: papain
*: ficain
*: bromelain (stem)
*: bromelain (juice)
*: chymopapain
*: asclepain
*: clostripain
*: yeast proteinase B
*: streptopain
*: insulinase
*: gamma-glutamyl hydrolase
*: staphylococcal cysteine proteinase
*: actinidain
*: cathepsin L
*: cathepsin H
*: calpain
*: prolyl endopeptidase (thiol-dependent)
*: endo-oligopeptidase
*: dinorphin-converting enzyme
*: yeast cysteine proteinase E
*: yeast cysteine proteinase D
*: yeast cysteine proteinase F
*: Cathepsin T
*: Glycyl endopeptidase
*: Cancer procoagulant
*: cathepsin S
*: picornain 3C
*: picornain 2A
*: Caricain
*: Ananain
*: Stem bromelain
*: Fruit bromelain
*: Legumain
*: Histolysain
*: caspase-1
*: Gingipain R
*: Cathepsin K
*: adenain
*: bleomycin hydrolase
*: cathepsin F
*: cathepsin O
*: cathepsin V
*: nuclear-inclusion-a endopeptidase
*: helper-component proteinase
*: L-peptidase
*: gingipain K
*: staphopain
*: separase
*: V-cath endopeptidase
*: cruzipain
*: calpain-1
*: calpain-2

EC 3.4.23 Aspartic endopeptidases

*: pepsin A
*: pepsin B
*: gastricsin
*: chymosin
*: cathepsin D
*: microbial carboxyl proteinases
*: Penicillium janthinellum acid proteinase
*: yeast proteinase A
*: rhizopus acid proteinase
*: endothia acid proteinase
*: thyroid aspartic proteinase
*: nepenthesin
*: Lotus aspartic proteinase
*: sorghum aspartic proteinase
*: renin
*: HIV-1 retropepsin
*: Pro-opiomelanocortin converting enzyme
*: Aspergillopepsin I
*: Aspergillopepsin II
*: Penicillopepsin
*: Rhizopuspepsin
*: Endothiapepsin
*: Mucorpepsin
*: Candidapepsin
*: Saccharopepsin
*: Rhodotorulapepsin
*: physaropepsin
*: Acrocylindropepsin
*: Polyporopepsin
*: Pycnoporopepsin
*: Scytalidopepsin A
*: Scytalidopepsin B
*: xanthomonapepsin
*: Cathepsin E
*: Barrierpepsin
*: Signal peptidase II
*: pseudomonapepsin
*: plasmepsin I
*: plasmepsin II
*: Phytepsin
*: yapsin 1
*: thermopsin
*: prepilin peptidase
*: nodavirus endopeptidase
*: memapsin 1
*: memapsin 2
*: HIV-2 retropepsin
*: plasminogen activator Pla

EC 3.4.24: Metallopeptidases

*: atrolysin A
*: Sepia proteinase
*: microbial collagenase
*: microbial metalloproteinases
*: lens neutral proteinase
*: leucolysin
*: interstitial collagenase
*: Achromobacter iophagus collagenase
*: Trichophyton schoenleinii collagenase
*: Trichophyton mentagrophytes keratinase
*: neprilysin
*: envelysin
*: IgA-specific metalloendopeptidase
*: procollagen N-endopeptidase
*: thimet oligopeptidase
*: neurolysin
*: stromelysin 1
*: meprin A
*: procollagen C-endopeptidase
*: peptidyl-Lys metalloendopeptidase
*: astacin
*: stromelysin 2
*: matrilysin
*: gelatinase A
*: vibriolysin
*: pseudolysin
*: thermolysin
*: bacillolysin
*: aureolysin
*: coccolysin
*: mycolysin
*: beta-Lytic metalloendopeptidase
*: peptidyl-Asp metalloendopeptidase
*: neutrophil collagenase
*: gelatinase B
*: leishmanolysin
*: saccharolysin
*: gametolysin
*: deuterolysin
*: serralysin
*: atrolysin B
*: atrolysin C
*: atroxase
*: atrolysin E
*: atrolysin F
*: adamalysin
*: horrilysin
*: ruberlysin
*: bothropasin
*: bothrolysin
*: ophiolysin
*: trimerelysin I
*: trimerelysin II
*: mucrolysin
*: pitrilysin
*: insulysin
*: O-sialoglycoprotein endopeptidase
*: russellysin
*: mitochondrial intermediate peptidase
*: dactylysin
*: nardilysin
*: magnolysin
*: meprin B
*: mitochondrial processing peptidase
*: macrophage elastase
*: choriolysin L
*: choriolysin H
*: tentoxilysin
*: bontoxilysin
*: oligopeptidase A
*: endothelin-converting enzyme 1
*: fibrolase
*: jararhagin
*: fragilysin
*: lysostaphin
*: flavastacin
*: snapalysin
*: gpr endopeptidase
*: pappalysin-1
*: membrane-type matrix metalloproteinase-1
*: ADAM10 endopeptidase
*: ADAMTS-4 endopeptidase
*: anthrax lethal factor endopeptidase
*: Ste24 endopeptidase
*: S2P endopeptidase
*: ADAM 17 endopeptidase

EC 3.4.25 Threonine endopeptidases

*: proteasome endopeptidase complex

EC 3.4.99 Endopeptidases of unknown catalytic mechanism

*: acrocylindricum proteinase
*: agavain
*: angiotensinase
*: aspartylendopeptidase
*: Clostridium histolyticum collagenase 2
*: crayfish low-molecular-weight proteinase
*: euphorbain
*: Gliocladium proteinase
*: hurain
*: insulinase
*: Streptomyces alkalophilic keratinase
*: Trichophyton mentagrophytes keratinase
*: beta-lytic proteinase (Mycobacterium sorangium)
*: mexicanain
*: Paecilomyces proteinase
*: Penicillium notatum extracellular proteinase
*: peptidoglycan endopeptidase
*: pinguinain
*: renin
*: scopulariopsis proteinase
*: solanain
*: staphylokinase
*: tabernamontanain
*: Tenebrio alpha-proteinase
*: trametes acid proteinase
*: urokinase
*: Echis carinatus prothrombin-activating proteinase
*: Oxyuranus scutellatus prothrombin-activating proteinase
*: Myxobacter AL-1 proteinase I
*: Myxobacter AL-1 proteinase II
*: Tissue endopeptidase degrading collagenase synthetic substrate
*: Armillaria mellea neutral proteinase
*: cathepsin R
*: mytilidase
*: premurein-leader peptidase
*: leader peptidase
*: RecA peptidase
*: pro-opiomelanotropin-converting proteinase
*: pseudomurein endopeptidase
*: pro-gonadoliberin proteinase
*: mitochondrial processing peptidase
*: leucyllysine endopeptidase
*: thermopsin
*: pitrilysin
*: insulinase
*: multicatalytic endopeptidase complex

EC 3.5: act on carbon-nitrogen bonds, other than peptide bonds

*: asparaginase
*: glutaminase
*: omega-amidase
*: amidase
*: urease
*: beta-ureidopropionase
*: ureidosuccinase
*: formylaspartate deformylase
*: arylformamidase
*: formyltetrahydrofolate deformylase
*: penicillin amidase
*: biotinidase
*: aryl-acylamidase
*: aminoacylase
*: aspartoacylase
*: acetylornithine deacetylase
*: acyl-lysine deacylase
*: succinyl-diaminopimelate desuccinylase
*: nicotinamidase
*: citrullinase
*: N-acetyl-beta-alanine deacetylase
*: pantothenase
*: ceramidase
*: choloylglycine hydrolase
*: N-acetylglucosamine-6-phosphate deacetylase
*: N4-(beta-N-acetylglucosaminyl)-L-asparaginase
*: N-formylmethionylaminoacyl-tRNA deformylase
*: N-acetylmuramoyl-L-alanine amidase
*: 2-(acetamidomethylene)succinate hydrolase
*: 5-aminopentanamidase
*: formylmethionine deformylase
*: hippurate hydrolase
*: N-acetylglucosamine deacetylase
*: acetylhistidine deacetylase
*: D-glutaminase
*: N-methyl-2-oxoglutaramate hydrolase
*: 4-L-aspartylglycosylamine amidohydrolase
*: glutamin-(asparagin-)ase
*: alkylamidase
*: acylagmatine amidase
*: chitin deacetylase
*: nicotinamide-nucleotide amidase
*: peptidyl-glutaminase
*: protein-glutamine glutaminase
*: urease (ATP-hydrolysing)
*: 6-aminohexanoate-dimer hydrolase
*: N-acetyldiaminopimelate deacetylase
*: acetylspermidine deacetylase
*: formamidase
*: pentanamidase
*: 4-acetamidobutyryl-CoA deacetylase
*: peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase
*: N-carbamoylputrescine amidase
*: allophanate hydrolase
*: long-chain-fatty-acyl-glutamate deacylase
*: N,N-dimethylformamidase
*: tryptophanamidase
*: N-benzyloxycarbonylglycine hydrolase
*: N-carbamoylsarcosine amidase
*: N-(long-chain-acyl)ethanolamine deacylase
*: mimosinase
*: acetylputrescine deacetylase
*: 4-acetamidobutyrate deacetylase
*: Nalpha-benzyloxycarbonylleucine hydrolase
*: theanine hydrolase
*: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
*: 4-methyleneglutaminase
*: N-formylglutamate deformylase
*: glycosphingolipid deacylase
*: aculeacin-A deacylase
*: N-feruloylglycine deacylase
*: D-benzoylarginine-4-nitroanilide amidase
*: carnitinamidase
*: chenodeoxycholoyltaurine hydrolase
*: urethanase
*: Arylalkyl acylamidase
*: N-carbamoyl-D-amino acid hydrolase
*: Glutathionylspermidine amidase
*: Phthalyl amidase
*: N-acetylgalactosamine-6-phosphate deacetylase
*: N-acyl-D-amino-acid deacylase
*: N-acyl-D-glutamate deacylase
*: N-acyl-D-aspartate deacylase
*: biuret amidohydrolase
*: (S)-N-acetyl-1-phenylethylamine hydrolase
*: mandelamide amidase
*: N-carbamoyl-L-amino-acid hydrolase
*: peptide deformylase
*: N-acetylglucosaminylphosphatidylinositol deacetylase
*: adenosylcobinamide hydrolase
*: N-substituted formamide deformylase
*: pantetheine hydrolase
*: barbiturase
*: dihydropyrimidinase
*: dihydroorotase
*: carboxymethylhydantoinase
*: allantoinase
*: beta-lactamase
*: imidazolonepropionase
*: cephalosporinase
*: 5-oxoprolinase (ATP-hydrolysing)
*: creatininase
*: L-lysine-lactamase
*: 6-aminohexanoate-cyclic-dimer hydrolase
*: 2,5-dioxopiperazine hydrolase
*: N-methylhydantoinase (ATP-hydrolysing)
*: cyanuric acid amidohydrolase
*: maleimide hydrolase
*: hydroxyisourate hydrolase
*: arginase
*: guanidinoacetase
*: creatinase
*: allantoicase
*: formimidoylaspartate deiminase
*: arginine deiminase
*: guanidinobutyrase
*: formimidoylglutamase
*: allantoate deiminase
*: D-arginase
*: agmatinase
*: agmatine deiminase
*: formimidoylglutamate deiminase
*: amidinoaspartase
*: protein-arginine deiminase
*: methylguanidinase
*: Guanidinopropionase
*: dimethylargininase
*: ureidoglycolate hydrolase
*: diguanidinobutanase
*: Methylenediurea deaminase
*: proclavaminate amidinohydrolase
*: cytosine deaminase
*: adenine deaminase
*: guanine deaminase
*: adenosine deaminase
*: cytidine deaminase
*: AMP deaminase
*: ADP deaminase
*: aminoimidazolase
*: methenyltetrahydrofolate cyclohydrolase
*: IMP cyclohydrolase
*: pterin deaminase
*: dCMP deaminase
*: dCTP deaminase
*: deoxycytidine deaminase
*: guanosine deaminase
*: GTP cyclohydrolase I
*: adenosine-phosphate deaminase
*: ATP deaminase
*: phosphoribosyl-AMP cyclohydrolase
*: pyrithiamine deaminase
*: creatinine deaminase
*: 1-pyrroline-4-hydroxy-2-carboxylate deaminase
*: blasticidin-S deaminase
*: sepiapterin deaminase
*: GTP cyclohydrolase II
*: diaminohydroxyphosphoribosylaminopyrimidine deaminase
*: methenyltetrahydromethanopterin cyclohydrolase
*: S-adenosylhomocysteine deaminase
*: GTP cyclohydrolase IIa
*: dCTP deaminase (dUMP-forming)
*: nitrilase
*: ricinine nitrilase
*: cyanate hydrolase
*: cyanoalanine nitrilase
*: arylacetonitrilase
*: bromoxynil nitrilase
*: aliphatic nitrilase
*: thiocyanate hydrolase
*: riboflavinase
*: thiaminase
*: hydroxydechloroatrazine ethylaminohydrolase
*: N-isopropylammelide isopropylaminohydrolase
*: 2-aminomuconate deaminase
*: glucosamine-6-phosphate deaminase
*: 1-aminocyclopropane-1-carboxylate deaminase

EC 3.6: act on acid anhydrides

*: inorganic diphosphatase
*: trimetaphosphatase
*: adenosinetriphosphatase
*: adenosinetriphosphatase (Mg-activated)
*: apyrase
*: nucleoside-diphosphatase
*: acylphosphatase
*: ATP diphosphatase
*: nucleotide diphosphatase
*: endopolyphosphatase
*: exopolyphosphatase
*: dCTP diphosphatase
*: ADP-ribose diphosphatase
*: adenosine-tetraphosphatase
*: nucleoside-triphosphatase
*: CDP-glycerol diphosphatase
*: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
*: FAD diphosphatase
*: nucleoside-triphosphate diphosphatase
*: 5'-acylphosphoadenosine hydrolase
*: ADP-sugar diphosphatase
*: NAD+ diphosphatase
*: dUTP diphosphatase
*: nucleoside phosphoacylhydrolase
*: triphosphatase
*: CDP-diacylglycerol diphosphatase
*: undecaprenyl-diphosphatase
*: thiamine-triphosphatase
*: bis(5'-adenosyl)-triphosphatase
*: m7G(5')pppN diphosphatase
*: phosphoribosyl-ATP diphosphatase
*: myosin ATPase
*: dynein ATPase
*: H+-transporting ATP synthase
*: H+-transporting ATPase
*: H+/K+ exchanging ATPase
*: Na+/K+ exchanging ATPase
*: Ca2+-transporting ATPase
*: thymidine-triphosphatase
*: guanosine-5'-triphosphate,3'-diphosphate diphosphatase
*: bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
*: guanosine-diphosphatase
*: dolichyldiphosphatase
*: oligosaccharide-diphosphodolichol diphosphatase
*: UDP-sugar diphosphatase
*: heterotrimeric G-protein GTPase
*: small monomeric GTPase
*: protein-synthesizing GTPase
*: dynamin GTPase
*: tubulin GTPase
*: diphosphoinositol-polyphosphate diphosphatase
*: adenylylsulfatase
*: phosphoadenylylsulfatase
*: phospholipid-translocating ATPase
*: Mg2+-importing ATPase
*: Cd2+-exporting ATPase
*: Cu2+-exporting ATPase
*: Zn2+-exporting ATPase
*: H+-exporting ATPase
*: Na+-exporting ATPase
*: Ca2+-transporting ATPase
*: Na+/K+-exchanging ATPase
*: H+/K+-exchanging ATPase
*: Cl-transporting ATPase
*: K+-transporting ATPase
*: H+-transporting two-sector ATPase
*: Na+-transporting two-sector ATPase
*: arsenite-transporting ATPase
*: monosaccharide-transporting ATPase
*: oligosaccharide-transporting ATPase
*: maltose-transporting ATPase
*: glycerol-3-phosphate-transporting ATPase
*: polar-amino-acid-transporting ATPase
*: nonpolar-amino-acid-transporting ATPase
*: oligopeptide-transporting ATPase
*: nickel-transporting ATPase
*: sulfate-transporting ATPase
*: nitrate-transporting ATPase
*: phosphate-transporting ATPase
*: phosphonate-transporting ATPase
*: molybdate-transporting ATPase
*: Fe3+-transporting ATPase
*: polyamine-transporting ATPase
*: quaternary-amine-transporting ATPase
*: vitamin B12-transporting ATPase
*: iron-chelate-transporting ATPase
*: manganese-transporting ATPase
*: taurine-transporting ATPase
*: guanine-transporting ATPase
*: capsular-polysaccharide-transporting ATPase
*: lipopolysaccharide-transporting ATPase
*: teichoic-acid-transporting ATPase
*: heme-transporting ATPase
*: beta-glucan-transporting ATPase
*: peptide-transporting ATPase
*: xenobiotic-transporting ATPase
*: steroid-transporting ATPase
*: cadmium-transporting ATPase
*: fatty-acyl-CoA-transporting ATPase
*: alpha-factor-transporting ATPase
*: channel-conductance-controlling ATPase
*: protein-secreting ATPase
*: mitochondrial protein-transporting ATPase
*: chloroplast protein-transporting ATPase
*: Ag+-exporting ATPase
*: myosin ATPase
*: dynein ATPase
*: microtubule-severing ATPase
*: plus-end-directed kinesin ATPase
*: minus-end-directed kinesin ATPase
*: vesicle-fusing ATPase
*: peroxisome-assembly ATPase
*: proteasome ATPase
*: chaperonin ATPase
*: non-chaperonin molecular chaperone ATPase
*: nucleoplasmin ATPase
*: heterotrimeric G-protein GTPase
*: small monomeric GTPase
*: protein-synthesizing GTPase
*: signal-recognition-particle GTPase
*: dynamin GTPase
*: tubulin GTPase

EC 3.7: act on carbon-carbon bonds

*: oxaloacetase
*: fumarylacetoacetase
*: kynureninase
*: phloretin hydrolase
*: acylpyruvate hydrolase
*: acetylpyruvate hydrolase
*: beta-diketone hydrolase
*: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
*: 2-hydroxymuconate-semialdehyde hydrolase
*: cyclohexane-1,3-dione hydrolase

EC 3.8: act on halide bonds

*: alkylhalidase
*: 2-haloacid dehalogenase
*: haloacetate dehalogenase
*: thyroxine deiodinase
*: haloalkane dehalogenase
*: 4-chlorobenzoate dehalogenase
*: 4-chlorobenzoyl-CoA dehalogenase
*: atrazine chlorohydrolase
*: (R)-2-haloacid dehalogenase
*: 2-haloacid dehalogenase (configuration-inverting)
*: 2-haloacid dehalogenase (configuration-retaining)
*: di-isopropyl-fluorophosphatase

EC 3.9: act on phosphorus-nitrogen bonds

*: phosphoamidase

EC 3.10: act on sulfur-nitrogen bonds

*: N-sulfoglucosamine sulfohydrolase
*: cyclamate sulfohydrolase

EC 3.11: act on carbon-phosphorus bonds

*: phosphonoacetaldehyde hydrolase
*: phosphonoacetate hydrolase

EC 3.12: act on sulfur-sulfur bonds

*: trithionate hydrolase

EC 3.13: act on carbon-sulfur bonds

*: UDP-sulfoquinovose synthase
*: 5-deoxyribos-5-ylhomocysteinase
*: 2'-hydroxybiphenyl-2-sulfinate desulfinase


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