Clue cell

Clue cell

Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria.

They are a medical sign of bacterial vaginosis, particularly that caused by Gardnerella vaginalis,[1] a group of Gram-variable bacteria. This bacterial infection gives a foul, fishy smelling yellow/grey frothy vaginal discharge, also the vaginal pH is increased above 5.5. Normal vaginal pH varies around 4.5.

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