Opsoclonus

Opsoclonus
Opsoclonus
Classification and external resources
ICD-9 379.59

Opsoclonus refers to uncontrolled eye movement. Opsoclonus consists of rapid, involuntary, multivectorial (horizontal and vertical), unpredictable, conjugate fast eye movements without intersaccadic intervals. It is also referred to as saccadomania or reflexive saccade. The movements of opsoclonus may have a very small amplitude, appearing as tiny deviations from primary position.

Possible etiologies of opsoclonus include neuroblastoma and encephalitis in children, and breast, lung, or ovarian cancer in adults. Other considerations include multiple sclerosis, toxins, or medication effects. It can also be caused by a lesion in the omnipause neurons which tonically inhibit initiation of saccadic eye movement (until signaled by the superior colliculus) by blocking paramedian pontine reticular formation (PPRF) burst neurons in the midbrain. It frequently occurs along with myoclonus in opsoclonus myoclonus syndrome.

See also

External links



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Look at other dictionaries:

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  • Opsoclonus myoclonus syndrome — Classification and external resources DiseasesDB 31932 Opsoclonus Myoclonus Syndrome (OMS) is a rare neurological disorder of unknown causes which appears to be the result of an autoimmune process involving the nervous system. It is an extremely… …   Wikipedia

  • opsoclonus-myoclonus syndrome — a syndrome of movements of the eyes (opsoclonus) and trunk (myoclonus), occurring in conjunction with a number of conditions, including viral infections, trauma, drug toxicity, tumors, and hyperosmolar nonketotic coma. It also occurs as a… …   Medical dictionary

  • opsoclonus — Rapid, irregular, nonrhythmic movements of the eye in horizontal and vertical directions. [G. ops, opos, eye, + klonos, confused motion] * * * n. a series of erratic eye movements in any direction, which is seen in people with disease of the… …   Medical dictionary

  • opsoclonus — n. a series of erratic eye movements, resembling a large amplitude fast nystagmus and developing spontaneously, that is seen in people with disease of the cerebellum or other parts of the brain …   The new mediacal dictionary

  • paraneoplastic opsoclonus — opsoclonus occurring as part of the paraneoplastic type of opsoclonus myoclonus syndrome (see under syndrome) …   Medical dictionary

  • opsoclonus-myoclonus — see under syndrome …   Medical dictionary

  • opsoclonus-myoclonus — see under syndrome …   Medical dictionary

  • dancing eyes — opsoclonus …   Medical dictionary

  • опсоклонус — (opsoclonus; греч. ops глаз + клонус; син.: миоклонус глазной, синдром пляшущих глаз) гиперкинез глазных яблок в виде содружественных быстрых, нерегулярных, неравномерных по амплитуде их движений, обычно в горизонтальной плоскости, наиболее… …   Большой медицинский словарь

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