Vertigo (medical)

Vertigo (medical)

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB =
ICD10 =
ICD9 = ICD9|438.85
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = neuro
eMedicineTopic =
MeshID =

Vertigo (from the Latin "vertere", to turn, and the suffix "-igo", a condition, i. e., "a condition of turning about" [cite web |url=http://www.m-w.com/dictionary/vertigo |title=Definition of vertigo - Merriam-Webster Online Dictionary |accessdate=2007-09-19 |format= |work=] ) is a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is actually stationary with respect to the surroundings.

There are two types of vertigo: subjective and objective. There is a "subjective" vertigo when a person has a false sensation of movement. In the case of "objective vertigo", the surroundings appear to move past a person's field of vision.

The effects of vertigo may be slight. It can cause nausea and vomiting and, in severe cases, it may give rise to difficulties with standing and walking.

Causes

Vertigo is usually associated with a problem in the inner ear balance mechanisms (vestibular system), in the brain, or with the nerve connections between these two organs.

Vertigo can be a symptom of an inner ear infection or of an underlying harmless cause. The most common cause of Vertigo is benign paroxysmal positional vertigo, or BPPV; however, vertigo can indicate the existence of more serious problems, including drug toxicities (specifically gentamicin), strokes or tumors (though these are much less common than BPPV), and syphilis.

Vertigo can also be a symptom of multiple sclerosis (MS). People with MS can feel off balance or lightheaded.

Vertigo can also be brought on suddenly through various actions or incidents, such as skull fractures or brain trauma, sudden changes of blood pressure, or as a symptom of motion sickness while sailing, riding amusement rides, aeroplanes or in a motor vehicle. Vertigo can also be caused by carbon monoxide poisoning. It is also one of the more common symptoms of superior canal dehiscence syndrome and Meniere's disease.

Vertigo-like symptoms may also appear as paraneoplastic syndrome (PNS) in the form of opsoclonus myoclonus syndrome, a multi-faceted neurological disorder associated with many forms of incipient cancer lesions or viruses.

Vertigo is typically classified into one of two categories depending on the location of the damaged vestibular pathway. These are peripheral or central vertigo. Each category has a distinct set of characteristics and associated findings.

Vertigo can also occur after long flights or boat journeys where the mind gets used to turbulence, resulting in a person's feeling as if he is moving up and down. This usually subsides after a few days.

There is also documented evidence that Genital Warts can cause it.Fact|date=October 2008

Neurochemistry

The neurochemistry of vertigo includes 6 primary neurotransmitters that have been identified between the 3-neuron arc that drives the vestibulo-ocular reflex (VOR). Many others play more minor roles.

Three neurotransmitters that work peripherally and centrally include glutamate, acetylcholine, and GABA.

Glutamate maintains the resting discharge of the central vestibular neurons, and may modulate synaptic transmission in all 3 neurons of the VOR arc. Acetylcholine appears to function as an excitatory neurotransmitter in both the peripheral and central synapses. GABA is thought to be inhibitory for the commissures of the medial vestibular nucleus, the connections between the cerebellar Purkinje cells and the lateral vestibular nucleus, and the vertical VOR.

Three other neurotransmitters work centrally. Dopamine may accelerate vestibular compensation. Norepinephrine modulates the intensity of central reactions to vestibular stimulation and facilitates compensation. Histamine is present only centrally, but its role is unclear. It is known that centrally acting antihistamines modulate the symptoms of motion sickness.

The neurochemistry of emesis overlaps with the neurochemistry of motion sickness and vertigo. Acetylcholine, histamine, and dopamine are excitatory neurotransmitters, working centrally on the control of emesis. GABA inhibits central emesis reflexes. Serotonin is involved in central and peripheral control of emesis but has little influence on vertigo and motion sickness.

Diagnostic testing

Tests of vestibular system (balance) function include electronystagmography (ENG), rotation tests, Caloric reflex test, [cite web |url=http://www.bcm.edu/oto/studs/vertigo.html |title=Core Curriculum: Inner Ear Disease - Vertigo |accessdate=2007-09-19 |format= |work=] and Computerized Dynamic Posturography (CDP). Tests of auditory system (hearing) function include pure-tone audiometry, speech audiometry, acoustic-reflex, electrocochleography (ECoG), otoacoustic emissions (OAE), and auditory brainstem response test (ABR; also known as BER, BSER, or BAER). Other diagnostic tests include magnetic resonance imaging (MRI) and computerized axial tomography (CAT or CT).

Treatment

Treatment is specific for underlying disorder of vertigo:

*vestibular rehabilitation
*anticholinergics
*antihistamines
*benzodiazepines
*calcium channel antagonists, specifically Verapamil and Nimodipine
*GABA modulators, specifically gabapentin and baclofen
*neurotransmitter reuptake inhibitors such as SSRI's, SNRI's and tricyclics
*benign paroxysmal positional vertigo (BPPV), a special kind of vertigo, is treated with the Epley maneuver (performed by a doctor or physical therapist, or with a BPPV maneuver at home)

References

External links

*
* [http://www.undiag.com/symptoms/vertigo.php Vertigo information]
* [http://www.vertigocure.org Vertigo Information - Causes, Symptoms, Treatment]


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Vertigo — may refer to: * Vertigo (medical), a form of dizziness * Vertigo (film), a film by Alfred Hitchcock **Vertigo effect, a special effect in film, named after the movie ** Vertigo (film score), its soundtrack * Vertigo (genus), a genus of snails *… …   Wikipedia

  • vértigo — m. neurol. Falsa sensación de movimiento; puede presentarse de dos formas distintas: un desplazamiento de los objetos en relación con el sujeto (vértigo objetivo), o del sujeto en relación con los objetos (vértigo subjetivo). Generalmente es… …   Diccionario médico

  • Medical sign — A medical sign is an objective[1] indication of some medical fact or characteristic that may be detected by a physician during a physical examination of a patient.[2] Signs may have no meaning for, and can even go unnoticed by, the patient, but… …   Wikipedia

  • Benign paroxysmal positional vertigo — Classification and external resources Exterior of labyrinth. ICD 10 H …   Wikipedia

  • Glossary of medical terms related to communications disorders — This is a glossary of medical terms related to communications disorders such as blindness and deafness. NOTOC A B C D E F G H I J K L M N O P Q R S T U V W X Y Z A Acoustic neuroma tumor, usually benign, which may develop on the hearing and… …   Wikipedia

  • Mr Vertigo — Auteur Paul Auster Genre Roman Version originale Titre original Mr. Vertigo Éditeur original Faber Faber Langue originale …   Wikipédia en Français

  • Flicker vertigo — is an imbalance in brain cell activity caused by exposure to low frequency flickering (or flashing) of a relatively bright light [ [http://www.flightsafety.org/members/serveme.cfm?path=hf/hf mar apr04.pdf (online article requires logon)] Clarence …   Wikipedia

  • Mr. Vertigo — Pour les articles homonymes, voir Vertigo. Mr Vertigo est un roman baroque de Paul Auster, qui se déroule dans l Amérique de 1927. Synopsis Walt, personnage principal, est un jeune orphelin élevé par un oncle méchant et une tante indifférente. À… …   Wikipédia en Français

  • Vincent van Gogh's medical condition — There is no consensus on the medical condition of Vincent van Gogh. Many competing hypotheses have been put forward. These include epilepsy, bipolar disorder, sunstroke, acute intermittent porphyria, lead poisoning and Ménière s disease. Symptoms …   Wikipedia

  • Kuon (video game) — Infobox VG| title = Kuon Japanese Cover| developer = From Software publisher = flagicon|Japan From Software flagicon|USA Agetec flagicon|EU Acclaim designer = Atsushi Taniguchi engine = released = flagicon|Japan April 1, 2004 flagicon|USA… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”