Macrocytosis

Macrocytosis

Infobox_Disease
Name = Macrocytosis


Caption =
DiseasesDB = 7688
ICD10 = ICD10|D|75|8|d|70
ICD9 = ICD9|289.89
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1381
MeshName =
MeshNumber =

Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).

Causes

Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include:

* Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs)
* hypothyroidism
* reticulocytosis (commonly from hemolysis or a recent history of blood loss).
* liver disease
* myeloproliferative disease

Complications

No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology.


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Look at other dictionaries:

  • macrocytosis — n. An abnormal physiological condition characterized by the presence of macrocytes in the blood. [WordNet 1.5] …   The Collaborative International Dictionary of English

  • macrocytosis — SYN: macrocythemia. [macrocyte + G. osis, condition] * * * mac·ro·cy·to·sis .mak rə sī tō səs, rə sə n, pl to·ses .sēz the occurrence of macrocytes in the blood * * * n. the presence of abnormally large red cells (macrocytes) in the blood.… …   Medical dictionary

  • macrocytosis — n. the presence of abnormally large red cells (macrocytes) in the blood. Macrocytosis is a feature of certain anaemias (macrocytic anaemias), including those due to deficiency of vitamin B12 or folic acid, and also of anaemias in which there is… …   The new mediacal dictionary

  • macrocytosis — noun (plural macrocytoses) Etymology: New Latin Date: circa 1893 the occurrence of macrocytes in the blood …   New Collegiate Dictionary

  • macrocytosis — mac·ro·cy·to·sis (măk rō sī tōʹsĭs) n. pl. mac·ro·cy·to·ses ( sēz) The presence of macrocytes in the blood.   mac ro·cy·totʹic ( tŏtʹĭk) adj. * * * …   Universalium

  • macrocytosis — noun The presence of macrocytes in the blood …   Wiktionary

  • macrocytosis — mac·ro·cy·to·sis …   English syllables

  • macrocytosis — noun the presence of macrocytes in the blood • Hypernyms: ↑pathology …   Useful english dictionary

  • Макроцитоз (Macrocytosis) — наличие в крови аномально больших по размеру эритроцитов (макроцитов (macrocytes)). Макроцитоз является одним из симптомов некоторых видов анемий (макроцитарных анемий (macrocytic anaemias)), в том числе тех, которые вызваны недостаточным… …   Медицинские термины

  • макроцитоз — (macrocytosis; макроцит + оз) преобладание макроцитов среди эритроцитов периферической крови …   Большой медицинский словарь

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