Serge Carrière

Dr. Serge Carrière O.C., M.D., C.S.P.Q., F.R.C.P.(C), is a Canadian physiologist, physician and educator. .^[1]

Born in Montreal, Quebec on July 21, 1934, he studied at the Université de Montréal, taking his B.A. in 1954 and his M.D. in 1959. He is married with four children. He did his internship at Notre-Dame hospital in Montreal and his residence there in internal medicine. In 1962, he joined the Harvard Medical School as an instructor in physiology from 1962 to 1964. Afterwards, he moved back to Montreal to set up his practice, specializing in nephrology. At the same time, he began teaching at the Université de Montréal's Faculty of Medicine, becoming an assistant professor in 1964, an associate professor in 1970, full professor in 1974 and Chairman of the Department of Physiology from 1980 to 1986. He then would rise to Chairman of the Department of Medicine until 1988, when he was named the dean of the Faculty. He served as dean until 1995. After his retirement from the post, he became Vice President of Clinical Research at Phoenix International Life Sciences and became President & C.O.O. from 1996 to 1997.

In 1997, he received the Order of Canada. He is also a recipient of many scientific and medical awards and honours including the G. Malcolm Brown Award. He has held several prestigious positions within the medical community as a Fellow and a Member of the Executive Committee of the Medical Research Council of Canada, President of the Quebec Health Research Fund, President of Louis Pasteur Canadian Foundation (CFLP)and Scientific Advisor of McGill University's Montreal Neurological Institute and Hospital.^[2]

A champion of academic freedom as an essential lever to fundamental medical and drug discovery, Dr. Carrière has played an instrumental role in biomedical education,^[3] research^[4] and biotechnology. He is co-founder of several biotechnology companies including Phoenix International Life Sciences Inc. where he served as President, Chief Operating officer and Vice-President of Clinical Research; and Lomedic which resulted in Theratechnology Inc. He was also Chief Executive Officer of the Canadian Medical Research Associates.

Throughout his career, Dr. Carrière has conducted extensive laboratory and clinical research^{[5][6] [7][8]} and continues to apply his expertise as a leading member of Bio-K Scientific Advisory Committee^[9] in collaboration with Dr. Pavel Hamet, Professor of Medicine and Canada Research Chair in Predictive Genomics and Director of Genomic Medicine at the University of Montreal Hospital Centre (CHUM). The University of Montreal held a special ceremony to thank Dr. Serge Carrière for his “Exemplary Generosity”.^[10]

References

1. ^ Carrière, Serge; Shao-Ling Zhanga, Catherine Toa, Xing Chena, Janos G. Filepa, Shiow-Shih Tangb, Julie R. Ingelfingerb, John S.D. Chana (2001). "Effect of Renin-Angiotensin System Blockade on the Expression of the Angiotensinogen Gene and Induction of Hypertrophy in Rat Kidney Proximal Tubular Cells". Experimental Nephrology (S. Karger AG, Basel) 9 (2): 9:109–117. doi:10.1159/000052601. http://content.karger.com/ProdukteDB/produkte.asp?Doi=52601. Retrieved December 1, 2008. 
2. ^ McPherson, PhD, Sandra (2008). Grey Matters Report 2005-2007 (Report). Montreal Neurological Institute and Hospital, McGill University. http://www.mni.mcgill.ca/files/media/MNI_AnnRep07_E.pdf. 
3. ^ Hawkins, David (2003). "National Principles for Crossovers and Transfers in Residency Programs Collaborative Principles Developed by ACMC's Standing Committee on Postgraduate Medical Education". ACMC Forum (The Association of Canadian Medical Colleges) 26 (3): 28. ISSN 836-3463. http://www.afmc.ca/pdf/2003_forum_sept.pdf. 
4. ^ Fustier, Pierre; Tusty-Jiuan Hsieh, Chih-Chang Wei1, Shao-Ling Zhang, Janos G Filep, Shiow-Shiu Tang, Julie R Ingelfinger, I George Fantus, Pavel Hamet and John S D Chan (14 September 2004). "Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells". Journal of Endocrinology (Society for Endocrinology) 183 (3): 535=550. doi:10.1677/joe.1.05871. PMID 15590980. http://circres.ahajournals.org/cgi/reprint/19/1/167.pdf?ck=nck. Retrieved December 1, 2008. 
5. ^ Carrière, Serge; Geoffrey D. Thorburn, Charles C. C. O'Morchoe and Clifford Barger (1966). "Intrarenal Distribution of Blood Flow in Dogs during Hemorrhagic Hypotension". Journal of the American Heart Association (American Heart association) 19: 14. ISSN 0009-7330. http://circres.ahajournals.org/cgi/reprint/19/1/167.pdf?ck=nck. Retrieved December 1, 2008. 
6. ^ Carrière, Serge; Harvey V. Sparks, Jr., Milton Hollenberg, Daniel Funkenstein, Richard M. Zakheim and A. Clifford Barger (1970). "Sympathomimetic drugs and repolarization of ventricular myocardium of the dog1". Cardiovascular Research (European Society of Cardiology) 4 (3): 8, 363–370. http://circres.ahajournals.org/cgi/reprint/19/1/167.pdf?ck=nck. Retrieved December 1, 2008. 
7. ^ Carrière, Serge; ZHANG Shao-Ling; TO Catherine; XING CHEN; FILEP Janos G.; TANG Shiow-Shih; INGELFINGER Julie R.; CHAN John S. D. (1970). "Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells". Experimental nephrology (Karger, Basel) 4(3) (2): 8, 109–117. ISSN 1018-7782. http://cat.inist.fr/?aModele=afficheN&cpsidt=861489. Retrieved December 1, 2008. 
8. ^ Sachetelli, S; Q Liu, S-L Zhang, F Liu, T-J Hsieh, M-L Brezniceanu, D-F Guo, J G Filep, J R Ingelfinger, C D Sigmund, P Hamet, J S D Chan (March 1, 2006). "RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney". Kidney International (International Society of nephrology) 69 (6): 13, 1016–1029. doi:10.1038/sj.ki.5000210. PMID 16528251. http://www.nature.com/search/executeSearch?sp-q-9=KI&sp-q=RAS+blockade+decreases+blood+pressure+and&sp-c=10&sp-x-9=cat&sp-s=0&submit=go&sp-a=sp1001702d&sp-sfvl-field=subject%7Cujournal&sp-x-1=ujournal&sp-p-1=phrase&sp-p=all. Retrieved December 1, 2008. 
9. ^ Bio-K Scientific Advisory Committee members: Dr. Serge Carrière, Dr Pavel Hamet (U. of Montreal), Dr François-Marie Luquet (Expert in Microbiology, formerly a leading Research Scientist Pasteur Institute, Paris), Dr Barbara Levine (Co-Director of the Human Nutrition Program at Rockefeller University and Director of the Nutrition Information Center at New York Hospital-Weill Medical College of Cornell University), Dr. Khursheed N. Jeejeebhoy (Gastroenterologist, Emeritus Professor of Medicine at the University of Toronto and Director of Nutrition Support at St. Michael's Hospital in Toronto), Dr. Jeffrey S. Borer (Professor of Cardiovascular Medicine, Radiology and Cardiothoracic Surgery at Weill Medical College, Cornell University)http://www.biokplus.com/en/comite_scientifique.php
10. ^ Newsroom (March 6, 2006). "Ceremony to Recognize Dr. Serge Carrière's Contribution". Hebdomadaire d'information Forum (University of Montreal) 40 (21). http://www.iforum.umontreal.ca/Forum/2005-2006/20060306/actualites04.html. Retrieved December 1, 2008. 

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