Cerato-platanin

Cerato-platanin
Identifiers
Symbol	Cerato-platanin
Pfam	PF07249
Pfam clan	CL0199
InterPro	IPR010829
Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary

In molecular biology, the cerato-platanin family of proteins includes the phytotoxin cerato-platanin (CP) produced by the Ascomycete Ceratocystis fimbriata f. sp. platani. This toxin causes the severe plant disease: canker stain. This protein occurs in the cell wall of the fungus and is involved in the host-plane interaction and induces both cell necrosis and phytoalexin synthesis which is one of the first plant defense-related events. CP, like other fungal surface proteins, is able to self assemble in vitro.^[1] CP is a 120 amino acid protein, containing 40% hydrophobic residues. It contains four cysteine residues that form two disulphide bonds.^[2] The N-terminal region of CP is very similar to cerato-ulmin, a phytotoxic protein produced by the Ophiostoma species belonging to the hydrophobin family, which also self-assembles.^[3]

References

1. ^ Sbrana F, Bongini L, Cappugi G, Fanelli D, Guarino A, Pazzagli L, Scala A, Vassalli M, Zoppi C, Tiribilli B (September 2007). "Atomic force microscopy images suggest aggregation mechanism in cerato-platanin". Eur. Biophys. J. 36 (7): 727–32. doi:10.1007/s00249-007-0159-x. PMID 17431609. 
2. ^ Pazzagli L, Cappugi G, Manao G, Camici G, Santini A, Scala A (August 1999). "Purification, characterization, and amino acid sequence of cerato-platanin, a new phytotoxic protein from Ceratocystis fimbriata f. sp. platani". J. Biol. Chem. 274 (35): 24959–64. PMID 10455173. 
3. ^ Carresi L, Pantera B, Zoppi C, Cappugi G, Oliveira AL, Pertinhez TA, Spisni A, Scala A, Pazzagli L (October 2006). "Cerato-platanin, a phytotoxic protein from Ceratocystis fimbriata: expression in Pichia pastoris, purification and characterization". Protein Expr. Purif. 49 (2): 159–67. doi:10.1016/j.pep.2006.07.006. PMID 16931046. 

This article includes text from the public domain Pfam and InterPro IPR010829