Terazosin

Terazosin

drugbox
IUPAC_name = [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl) piperazin-1-yl] - tetrahydrofuran-2-yl-methanone


CAS_number = 63590-64-7
ATC_prefix = G04
ATC_suffix = CA03
ATC_supplemental =
PubChem = 5401
DrugBank = APRD00667
C=19 | H=25 | N=5 | O=4
molecular_weight = 387.433 g/mol
bioavailability =
protein_bound = 90-94%
metabolism =
elimination_half-life = 12 hours
pregnancy_category =
legal_status =
routes_of_administration =

Terazosin (Hytrin) is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefore a drug of choice for men with hypertension and prostate enlargement.

It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon. [ [http://www.rxlist.com/cgi/generic/teraz_wcp.htm Hytrin (Terazosin Hcl) drug warnings and precautions - prescription drugs and medications at RxList ] ] Sexual side effects are rare, but may include priapism or erectile dysfunction.

References


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Look at other dictionaries:

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  • terazosin — noun A selective alpha 1 antagonist that is used to help treat an enlarged prostate and to help lower blood pressure …   Wiktionary

  • terazosin — te·ra·zo·sin tə rā zə .sin n an alpha adrenergic blocking agent administered orally in the form of its hydrated hydrochloride C19H25N5O4·HCl·2H2O esp. in the treatment of benign prostatic hyperplasia and hypertension see hytrin …   Medical dictionary

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  • Doxazosin — Systematic (IUPAC) name (RS) 2 {4 [(2,3 dihydro 1,4 benzodioxin 2 yl)carbonyl]piperazin 1 yl} 6,7 dimethoxyquinazolin 4 amine Clinical data Trade names …   Wikipedia

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