KCNU1

KCNU1

protein
name=potassium channel, subfamily U, member 1
caption=


width=
HGNCid=18867
Symbol=KCNU1
AltSymbols=KCa5.1, Slo3, KCNMC1, Kcnma3
EntrezGene=157855
OMIM=
RefSeq=NM_001031836
UniProt=
PDB=
ECnumber=
Chromosome=8
Arm=p
Band=11.2
LocusSupplementaryData=

KCNU1 is a potassium channel.cite journal | author = Schreiber M, Wei A, Yuan A, Gaut J, Saito M, Salkoff L | title = Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes | journal = J. Biol. Chem. | volume = 273 | issue = 6 | pages = 3509–16 | year = 1998 | month = February | pmid = 9452476 | doi = 10.1074/jbc.273.6.3509 | url = | issn = ]

Although this channel is structurally related to the calcium-activated potassium channels, it cannot be classified as such since it is activated by high intracellular pH and relatively insensitive to changes in calcium concentrations.cite journal |author=Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H|title=International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels.|journal= Pharmacol Rev |volume= 57 |issue= 4 |pages= 463–72 |year= 2005 |pmid= 16382103 | doi = 10.1124/pr.57.4.9] cite journal | author = Zhang X, Zeng X, Xia XM, Lingle CJ | title = pH-regulated Slo3 K+ channels: properties of unitary currents | journal = J. Gen. Physiol. | volume = 128 | issue = 3 | pages = 301–15 | year = 2006 | month = September | pmid = 16940554 | pmc = 2151565 | doi = 10.1085/jgp.200609551 | url = | issn = ] cite journal | author = Zhang X, Zeng X, Lingle CJ | title = Slo3 K+ channels: voltage and pH dependence of macroscopic currents | journal = J. Gen. Physiol. | volume = 128 | issue = 3 | pages = 317–36 | year = 2006 | month = September | pmid = 16940555 | pmc = 2151566 | doi = 10.1085/jgp.200609552 | url = | issn = ]

References


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  • Calcium-activated potassium channel — Calcium activated potassium channels are divided into BK channels, IK channels, and SK channels based on their conductance (big, intermediate, and small conductance).This family of ion channels is, for the most part, activated by intracellular… …   Wikipedia

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