Lymphokine

Lymphokine

Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, like macrophages and other lymphocytes, to an infected site and their subsequent activation prepare them to attack the invaders. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required.

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  • lymphokine — [ lɛ̃fɔkin ] n. f. • v. 1975; de lympho et gr. kinein « mouvoir » ♦ Biol. Substance sécrétée par des lymphocytes T, qui active d autres globules blancs, y compris d autres lymphocytes. ⇒ interleukine. ● lymphokine nom féminin Substance libérée… …   Encyclopédie Universelle

  • Lymphokine — sind eine Sammelbezeichnung für spezielle Zytokine. Die ursprüngliche Definition von Dumonde (1982) bezeichnete alle nicht Antikörper Proteine, die von aktivierten Lymphozyten produziert werden und als interzellulare Botenstoffe der Immunantwort… …   Deutsch Wikipedia

  • Lymphokine —   [zu griechisch kineĩn »bewegen«] Plural, Immunologie: von Lymphozyten, v. a. T Lymphozyten, gebildete Zytokine …   Universal-Lexikon

  • Lymphokine — Lymphokine, von T Helfer Zellen und anderen Immunzellen sezernierte Glykoproteine, z.B. ⇒ Interleukine und ⇒ Interferone, die Abwehrvorgänge anregen …   Deutsch wörterbuch der biologie

  • lymphokine — [lim′fō kīn΄] n. [ LYMPHO + kine < Gr kinein, to move] any of various soluble proteins, as interferon, that are secreted by T cells interacting with an antigen and that help fight infection …   English World dictionary

  • lymphokine — limfokinas statusas T sritis chemija apibrėžtis Imuninės sistemos baltymas. atitikmenys: angl. lymphokine rus. лимфокин …   Chemijos terminų aiškinamasis žodynas

  • Lymphokine-activated killer cell — In cell biology, a lymphokine activated killer cell (also known as a LAK cell) is a white blood cell that has been stimulated to kill tumour cells. [cite web | url=http://www.cancer.gov/Templates/db alpha.aspx?CdrID=45287 | title=Definition of… …   Wikipedia

  • lymphokine — noun Etymology: lymph + kine, from Greek kinein to move about more at kinesis Date: 1969 any of various substances (as interleukin 2) of low molecular weight that are not antibodies, are secreted by T cells in response to stimulation by antigens …   New Collegiate Dictionary

  • lymphokine — (lim fo kin) A biologically active glycoprotein (e.g., IL 1) secreted by activated lymphocytes, especially sensitized T cells. It acts as an intercellular mediator of the immune response and transmits growth, differentiation, and behavioral… …   Dictionary of microbiology

  • lymphokine — Lackie Substance produced by a leucocyte that acts upon another cell. Examples are interleukins, interferon g, lymphotoxin (tumour necrosis factor b ), granulocyte monocyte colony stimulating factor (GM CSF). The term is becoming less common and… …   Dictionary of molecular biology

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