Articular cartilage damage

Cartilage structures and functions can be damaged. Such damage can result from a variety of causes, resulting from a bad fall or sport-accident (traumatic), previous knee injuries (post-traumatic) or wear and tear over time. Immobilisation for long periods can also result in cartilage damage.

Articular cartilage damage in the knee might be found on its own but it will more often be found in conjuction with injuries to ligaments and menisci. People with previous sergival interventions face more chances of articular cartilage damage due to altered mechanics of the joint.

Damage to the articular cartilage can be repaired.

Diagnosing articular cartilage damage (through Arthroscopy)

No non-invasive tests are currently able to diagnose articular cartilage damage. Aditionally, symptoms vary considerably from person to person. Or as [http://www.cartilagehealth.com/acr.html dr. Karen Hambly] would state it : "You may or may not have pain and you could have no, or limited, swelling. Yes you may experience locking if a piece of articular cartilage has broken off and is a loose body in the joint or you may experience catching or giving way. You are likely to have some muscle wasting and difficulty in activities such as going up and down stairs, walking or running but then people with any moderate knee injury are likely to as well. This is why articular cartilage damage is the ‘cinderella’ of knee problems. It tends to be diagnosed only after other structures have been ruled out – well if it isn’t your meniscus or ligaments, what else could it be, perhaps we should look at the articular cartilage?" [www.cartilagehealth.com/acr.html ]

MRI-scans are becoming more valuable in the analysis of articular cartilage but their use is still expensive and time consuming. X-rays only show bone injuries and are therefore not very helpful in diagnosing cartilage damage, especially not in early stages. The best tool for diagnosing articular damage is the use of arthroscopy.

=Measuring Cartilage Da

The [http://www.cartilage.org International Cartilage Repair Society] (ICRS) has set up an arthroscopic grading system by which cartilage defects can be ranked:

* grade 0: (normal) healthy cartilage
* grade 1: the cartilage has a soft spot or blisters
* grade 2: minor tears visible in the cartilage
* grade 3: lesions have deep crevices (more than 50% of cartilage layer)
* grade 4: the cartilage tear exposes the underlying (subchronal) bone

Doctors will often also measure the size of each defect. Defects smaller than 2 cm², for example, are considered to be small. It is also important to remember that although the amount of damage is an important factor, the location of the defect(s) can also influence the symptoms you are getting in terms of pain and function and their repair options available. ["Articular Cartilage Repair of the Knee" Karen Hambly, www.cartilagehealth.com/acr.html]

In contrast to popular perception, pain is not a good indicator for determining the extent of articular cartilage damage. One person can have severe pain with a single small defect while another person can have very little pain with several large full thickness defects. ["Articular Cartilage Repair of the Knee" Karen Hambly, www.cartilagehealth.com/acr.html]

=Consequences of cartilage da

Articular cartilage has a very limited capacity for self repair. Small damage does not repair itself and can often get worse over time. As cartilage is aneural and avascular (does not have nerve supply), shallow damage often does not trigger pain.

When the damage increases an the chondral defect reaches the subchondral bone, the blood supply in the bone starts a healing process in the defect. Scar tissue made up of a type of cartilage called fibrocartilage is then formed. Although fibrocartilage is able to fill in articular cartilage defects its structure is significantly different to that of hyaline cartilage; it is much denser and it doesn't withstand the demands of everyday activities as much as hyaline cartilage. It is therefore at a higher risk of breaking down. [Hambley K. "Articular cartilage repair of the knee" www.kartilagehealth.com/acr.html]

Wang (2006) found that small articular cartilage defects can progress to osteoarthritis over time if left untreated. [Wang, Y., Ding, C., Wluka, A. E., Davis, S., Ebeling, P. R., Jones, G. and Cicuttini, F. M. (2006) Factors affecting progression of knee cartilage defects in normal subjects over 2 years. Rheumatology, 45(1): 79-84. [http://rheumatology.oxfordjournals.org/cgi/content/abstract/45/1/79] ] An articular cartilage defect that initially may be small still has the potential to have a physical and chemical "domino effect" on the surrounding "normal" articular cartilage. [Hambley K. "Articular cartilage repair of the knee" www.kartilagehealth.com/acr.html]

=Repairing articular cartilage da

Though articular cartilage damage is not life threatening, it does strongly affect one's quality of life. Articular cartilage damage is often the cause of severe pain, knee swelling, substantial reduction in mobility and severe restrictions to one's activities. Over the last decades, however, research has focussed on regenerating damaged joints.

These regenerative procedures are believed to delay osteoarthritis of injuries on the articular cartilage of the knee, by slowing down the degeneration of the joint compared to untreated damage. [Hambley K. "Articular cartilage repair of the knee" [www.cartilagehealth.com/acr.html] ] According to Dr. Mithoefer, these articular cartilage repair procedures offer the best results when the intervention takes place in the early stages of the cartilage damage. [Mithoefer K. "High impact athletics after knee articular cartilage repair". American Journal of Sports Medicine vol 34 issue 9 pp 1413-1418, September 2005]

References