Hydroflumethiazide

Hydroflumethiazide: Hydroflumethiazide

Systematic (IUPAC) name

1,1-Dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide

Clinical data

AHFS/Drugs.com Micromedex Detailed Consumer Information

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 135-09-1

ATC code C03AA02

PubChem CID 3647

DrugBank DB00774

ChemSpider 3521^Y

UNII 501CFL162R^Y

KEGG D00654^Y

ChEMBL CHEMBL1763^Y

Chemical data

Formula C₈H₈F₃N₃O₄S₂

Mol. mass 331.29 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16)^Y
Key:DMDGGSIALPNSEE-UHFFFAOYSA-N^Y

Y(what is this?) (verify)

Hydroflumethiazide (or Saluron) is a diuretic.

v · d · eSymporter inhibitors

Sodium chloride
thiazide: Bendroflumethiazide • Chlorothiazide • Cyclopenthiazide • Cyclothiazide • Hydrochlorothiazide • Hydroflumethiazide • Methyclothiazide • Polythiazide • Trichlormethiazide
other: Chlorthalidone • Metolazone

Sodium, potassium, chloride
Bumetanide • Furosemide

v · d · eAntihypertensives: diuretics (C03)

Sulfonamides
(except EA)

CA inhibitors (at PT)

Acetazolamide

Loop (Na-K-Cl at AL)

Furosemide^# • Bumetanide • Torasemide • Etacrynic acid

Thiazides (Na-Cl at DCT,
Calcium-sparing)

Hydrochlorothiazide^# • Bendroflumethiazide • Hydroflumethiazide • Chlorothiazide • Polythiazide • Trichlormethiazide • Cyclopenthiazide • Methyclothiazide • Cyclothiazide • Mebutizide

Thiazide-likes (primarily DCT)

Quinethazone • Clopamide • Chlortalidone • Mefruside • Clofenamide • Metolazone • Meticrane • Xipamide • Indapamide • Clorexolone • Fenquizone

Potassium-sparing (at CD)

ESC blockers

Amiloride^# • Triamterene • Benzamil

Aldosterone antagonists

Spironolactone^# • Eplerenone • Potassium canrenoate • Canrenone

Osmotic diuretics (PT, DL)
Mannitol^# • Urea

VAs (DCT and CD)

vaptans: Conivaptan • Mozavaptan • Satavaptan • Tolvaptan
tetracyclines: Demeclocycline

Other
mercurial diuretic (Mersalyl) • Theobromine • Cicletanine

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: VAS

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noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug(C2s+n/3/4/5/7/8/9)

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Hydroflumethiazide

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Systematic (IUPAC) name
1,1-Dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	135-09-1
ATC code	C03AA02
PubChem	CID 3647
DrugBank	DB00774
ChemSpider	3521^Y
UNII	501CFL162R^Y
KEGG	D00654^Y
ChEMBL	CHEMBL1763^Y
Chemical data
Formula	C₈H₈F₃N₃O₄S₂
Mol. mass	331.29 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C8H8F3N3O4S2/c9-8(10,11)4-1-5-7(2-6(4)19(12,15)16)20(17,18)14-3-13-5/h1-2,13-14H,3H2,(H2,12,15,16)^Y Key:DMDGGSIALPNSEE-UHFFFAOYSA-N^Y
Y(what is this?) (verify)

Academic Dictionaries and Encyclopedias

Wikipedia

Hydroflumethiazide

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