Plasmodium malariae

Plasmodium malariae

Taxobox
color = greenyellow
name = "Plasmodium malariae"



image_width = 240px
image_caption = Giemsa-stained micrograph of a mature "Plasmodium malariae"
regnum = Protista
phylum = Apicomplexa
classis = Aconoidasida
ordo = Haemosporida
familia = Plasmodiidae
genus = "Plasmodium"
species = "P. malariae"
binomial = "Plasmodium malariae"
binomial_authority = Feletti & Grassi, 1889

"Plasmodium malariae" is a parasitic protozoa that causes malaria in humans and animals. It is closely related to "Plasmodium falciparum" and "Plasmodium vivax" which are responsible for most malarial infection. While found worldwide, it is a so-called "benign malaria" and is not nearly as dangerous as that produced by "P. falciparum" or "P. vivax". "P. malariae" causes fevers that recur at approximately three-day intervals (a "quartan fever"), longer than the two-day (tertian) intervals of the other malarial parasites.

igns and symptoms

"Plasmodium malariae" causes a long-lasting, chronic infection that in some cases can last a lifetime. In some patients "P. malariae" can cause serious complications such as the nephrotic syndrome.

Due to a similarity in the appearances of the pathogens, "P. knowlesi" infections are often misdiagnosed as "P. malariae" infections. Molecular analysis is usually required for an accurate diagnosis cite journal | journal=Lancet | year=2004 | volume=363 | pages=1017–24 | title=A large focus of naturally acquired "Plasmodium knowlesi" infections in human beings | author=Singh B, Lee KS, Matusop A | doi=10.1016/S0140-6736(04)15836-4 ] .

Biology

Life cycle

"P. malariae" is the only human malaria parasite that causes fevers that recur at approximately three-day intervals (therefore occurring evey fourth day, a "quartan fever"), longer than the two-day ("tertian") intervals of the other malarial parasites.cite web
last =
first =
authorlink =
coauthors =
title = Biology: Malaria (CDC malaria)
work =
publisher =
date =
url = http://www.cdc.gov/malaria/biology/parasites/index.htm
format =
doi =
accessdate =
]

Human Infection

Liver Stage

Within the hepatocytes, the exoerythrocytic schizogony stage of "P. malariae" has a minimum duration of roughly 15 days.cite web
last =
first =
authorlink =
coauthors =
title = Malaria eModule - Exo-Erythrocytic Stages
work =
publisher =
date =
url = http://www.impact-malaria.com/FR/EPS/Formations_et_cours_internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_1/1_4.html
format =
doi =
accessdate =
]

Erythrocytic Cycle

The total length of the intraerythrocytic development is roughly 72 hours for "P. malariae".cite web
last =
first =
authorlink =
coauthors =
title = Malaria eModule - ASEXUAL ERYTHROCYTIC STAGES
work =
publisher =
date =
url = http://www.impact-malaria.com/FR/EPS/Formations_et_cours_internationaux/Formation_de_la_Liverpool_School_LSTMH/cours_liverpool/Unit_1/1_5.html
format =
doi =
accessdate =
]

At the schizont stage, after schizogonic division, there are roughly 6-8 parasite cells in the erythrocyte.

exual Stage

Mosquito Stage

Laboratory considerations

"P. vivax" and "P. ovale" that has been sitting in EDTA for more than half-an-hour before the blood film is made will look very similar in appearance to "P. malariae", which is an important reason to warn the laboratory immediately when the blood sample is drawn so they can process the sample as soon as it arrives.

Microscopically, the parasitised red blood cell (erythrocyte) is never enlarged and may even appear smaller than that of normal red blood cells. The cytoplasm is not decolorized and no dots are visible on the cell surface. The food vacuole is small and the parasite is compact. Cells seldom host more than one parasite. Band forms, where the parasite forms a thick band across the width of the infected cell, are characteristic of this species (and some would say is diagnostic). Large grains of malarial pigment are often seen in these parasites: more so than any other "Plasmodium" species. 8 merozoites

References


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Plasmodium malariae — Reifer Schizont von Plasmodium malariae im gefärbten Blutausstrich Systematik ohne Rang …   Deutsch Wikipedia

  • Plasmodium malariae — Plasmodium malariae …   Wikipédia en Français

  • Plasmodium malariae — Saltar a navegación, búsqueda ? Plasmodium malariae Plasmodium malariae esquizont …   Wikipedia Español

  • Plasmodium malariae — Plasmodium malariae …   Wikipédia en Français

  • Plasmodium malariae — Malaria parasite Malaria parasite Any of several minute protozoans of the genus {Plasmodium} (syn. {H[ae]matozo[ o]n}) which in their adult condition live in the tissues of mosquitoes of the genus {Anopheles} (which see) and when transferred to… …   The Collaborative International Dictionary of English

  • Plasmodium MALARIAE — вид P., характеризующийся 72 часовой продолжительностью шизогонии и являющийся возбудителем четырехдневной малярии человека …   Большой медицинский словарь

  • Plasmodium malariae — the species that causes quartan malaria; it is characterized by bandlike trophozoites and schizonts with six to twelve merozoites usually arranged in a rosette configuration …   Medical dictionary

  • Plasmodium malariae malaria — quartan m …   Medical dictionary

  • Plasmodium — Schizont von Plasmodium malariae, der Typusart der Gattung, im gefärbten Blutausstrich Systematik ohne Rang: Chromalveolata …   Deutsch Wikipedia

  • Plasmodium — Plasmodium …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”