calcineurin
Calmodulin-stimulated protein-phosphatase (EC 3.1.3.16), the major calmodulin-binding protein in brain. Enzymic activity is inhibited by binding of immunophilin-ligand complex (immunophilin alone does not bind) and therefore may play a part in the mechanism of action of cyclosporin A and FK506. Thought also to be involved in the control of sperm motility.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Calcineurin — Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • calcineurin — /kal si nū rin/ noun An enzyme which plays a role in many brain functions, abnormal levels of which are associated with schizophrenia ORIGIN: calcium, ↑neur with sfx in …   Useful english dictionary

  • Calcineurin — Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform, also known as PPP3CA, is a human gene.cite web | title = Entrez Gene: PPP3CA protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform| url =… …   Wikipedia

  • calcineurin — A calcium dependent serine threonine phosphatase involved in T cell signaling transcription; the reaction cascade in which it resides is referred to as the c. pathway. [calcium + G. neuron, nerve, + in] * * * cal·ci·neur·in (kal″sĭ… …   Medical dictionary

  • calcineurin — noun A protein phosphatase that stimulates the growth and differentiation of T cells …   Wiktionary

  • calcineurin inhibitor — any of a group of compounds that inhibit the action of calcineurin and are used as immunosuppressants …   Medical dictionary

  • PP2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • Protein-Phosphatase 2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • Protein Phosphatase 2B — Calcineurin Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

  • CABIN1 — Calcineurin binding protein 1, also known as CABIN1, is a human gene.cite web | title = Entrez Gene: CABIN1 calcineurin binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23523| accessdate =… …   Wikipedia

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