- bride of sevenless
(= boss)In Drosophila eye development, the ligand for the sevenless tyrosine kinase receptor. Boss is expressed by the central R8 cell. It is unusual as a ligand for a tyrosine receptor kinase in that it is on the surface of another cell and has, in addition to a large extracellular domain, seven transmembrane segments and a C-terminal cytoplasmic tail.
Dictionary of molecular biology. 2004.
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Sevenless — Drosophila gene that is required for development of the R7 cell in each ommatidium in the eye. Gene product is a receptor tyrosine kinase, related to the insulin receptor. Ligand is the product of the bride of sevenless gene. In the downstream… … Dictionary of molecular biology
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Class C GPCR — 7 transmembrane receptor (metabotropic glutamate family) Identifiers Symbol 7tm 3 Pfam PF00003 InterPro … Wikipedia