- brefeldin A
A macrocyclic lactone synthesized from palmitic acid by several fungi including Penicillium brefeldianum. It was initially described as an antiviral antibiotic, but it was later found to inhibit protein secretion at an early stage, probably blocking secretion in a pre-Golgi compartment. Its exact site of action is still a matter of debate, one suggestion being that it inhibits the binding of regulatory coat proteins to organellar membranes. Nevertheless, it has proved a valuable tool for studying membrane traffic and the control of organelle structure.
Dictionary of molecular biology. 2004.
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Brefeldin A — Strukturformel Allgemeines Name Brefeldin A Andere Namen … Deutsch Wikipedia
Brefeldin A — Chembox new ImageFile=Brefeldin a.png ImageSize= IUPACName=γ,4 Dihydroxy 2 (6 hydroxy 1 heptenyl) 4 cyclopentanecrotonic acid λ lactone OtherNames= Section1= Chembox Identifiers CASNo=20350 15 6 PubChem=24278285 SMILES= MeSHName= Section2=… … Wikipedia
brefeldin — noun Any of several lactone antibiotics produced by fungi … Wiktionary
ARFGEF1 — ADP ribosylation factor guanine nucleotide exchange factor 1 (brefeldin A inhibited), also known as ARFGEF1, is a human gene.cite web | title = Entrez Gene: ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1(brefeldin A… … Wikipedia
ARFGEF2 — ADP ribosylation factor guanine nucleotide exchange factor 2 (brefeldin A inhibited), also known as ARFGEF2, is a human gene.cite web | title = Entrez Gene: ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 (brefeldin A… … Wikipedia
GBF1 — Golgi specific brefeldin A resistance factor 1, also known as GBF1, is a human gene.cite web | title = Entrez Gene: GBF1 golgi specific brefeldin A resistance factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… … Wikipedia
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