bicuculline
From Dicentra cucullaria and herbs of the genus Corydalis. Specific blocking agent for the action of the amino acid transmitter g -aminobutyric acid (GABA). See amino acid transmitter; amino acid receptor superfamily, GABA receptor.

Dictionary of molecular biology. 2004.

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  • Bicuculline — drugbox IUPAC name = Bicuculline width = 200 height = 150 CAS number = 485 49 4 ATC prefix = ATC suffix = ATC supplemental = PubChem = 10237 DrugBank = smiles = C1=C6C(=CC2=C1CCN( [C@@H] 2 [C@H] 3C4C(C(O3)=O)C5=C(C=C4)OCO5)C)OCO6 C=20 | H=17 |… …   Wikipedia

  • bicuculline — noun A light sensitive competitive antagonist of GABA receptors; it is used in the study of epilepsy …   Wiktionary

  • bicuculline — An alkaloid naturally occurring in the d form; found in Dicentra cucullaria and Adlumia fungosa (family Fumariaceae) and several Corydalis species; a powerful convulsant that acts by antagonizing γ aminobutyric acid, an inhibitory… …   Medical dictionary

  • bicuculline — bi·cu·cul·line …   English syllables

  • bicuculline — (ˈ)bī¦k(y)ükyəˌlēn, lə̇n noun ( s) Etymology: bi (I) + cucull (from cucullaria, specific epithet of Dicentra cucullaria, Dutchman s breeches, in which the substance occurs) + ine : a convulsant alkaloid C20H17 …   Useful english dictionary

  • GABA receptor — The GABA receptors are a class of receptors that respond to the neurotransmitter γ aminobutyric acid (GABA), the chief inhibitory neurotransmitter in the vertebrate central nervous system. There are three classes of GABA receptors: GABAA, GABAB,… …   Wikipedia

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  • Glycine — For the plant, see Glycine (plant). Glycine[1] …   Wikipedia

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