Oncogene associated with some cases of B-cell chronic lymphocytic leukaemias. The protein product contains seven "ankyrin-repeats" very similar to those found in I k B. Seems to interfere with binding of 50 kD subunit of NF k B to DNA.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Bcl-2 — family[1] …   Wikipédia en Français

  • Bcl-2 — is the prototype for a family of mammalian genes and the proteins they produce. They govern mitochondrial outer membrane permeabilization (MOMP) and can be either pro apoptotic (Bax, BAD, Bak and Bok among others) or anti apoptotic (including Bcl …   Wikipedia

  • Bcl-2 — Saltar a navegación, búsqueda Bcl 2 (B cell CLL/lymphoma 2) Identificadores Símbolo BCL2 Entrez 596 HUGO …   Wikipedia Español

  • Bcl-2 — Struktur nach PDB  …   Deutsch Wikipedia

  • Bcl — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. {{{image}}}   Sigles d une seule lettre   Sigles de deux lettres > Sigles de trois lettres …   Wikipédia en Français

  • Bcl-2-associated death promoter — The Bcl 2 associated death promoter (BAD) protein is a pro apoptotic member of the Bcl 2 gene family which is involved in initiating apoptosis. It does not contain a C terminal transmembrane domain for outer mitochondrial membrane and nuclear… …   Wikipedia

  • Bcl-2-interacting killer — BCL2 interacting killer (apoptosis inducing), also known as BIK, is a human gene.cite web | title = Entrez Gene: BIK BCL2 interacting killer (apoptosis inducing)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Bcl-2-associated X protein — The Bcl 2–associated X protein, or BAX, gene was the first identified pro apoptotic member of the Bcl 2 protein family. [] Bcl 2 family members share one or more of the four characteristic domains of homology entitled the Bcl 2 homology (BH)… …   Wikipedia

  • Bcl-2 — BCL2 Обозначения Символы …   Википедия

  • Bcl-2-associated death promoter — BCL2 antagonist of cell death Größe 168 aa; 18,4 kDa Struktur Heterodimer Bezeichner …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”