Shorter of the two polypeptide chains of insulin (21 residues compared to 30 in the B chain). Many other heterodimeric proteins have their smaller chain designated the A chain, so the term cannot be used without qualification. Other A chains: abrin, activin, C1q (see complement), diphtheria toxin, inhibin, laminin, mistletoe lectin, PDGF, relaxin, ricin, TPA.

Dictionary of molecular biology. 2004.

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