- VLA proteins
(= very late antigens)VLA-1 and VLA-2 were originally defined as antigens appearing on the surfaces of T-lymphocytes 2-4 weeks after in vitro activation; they are now know to be part of the b integrin family. Additional members of the subset are now known (VLA-3, VLA-4, VLA-5 and VLA-6), the b subunits all being identical. Some of the VLA proteins are receptors for collagen, laminin or fibronectin, and many are now known to be expressed on cells other than leucocytes.
Dictionary of molecular biology. 2004.