variable antigen
Term usually applied to the surface antigens of those parasitic or pathogenic organisms that can alter their antigenic character to evade host immune responses. (See antigenic variation).

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • variable region — n the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free amino group NH2, that varies greatly in its sequence of amino acid residues from one antibody to another, and that prob. determines the conformation… …   Medical dictionary

  • Antigen - Antikörper - Bindung — Antikörper Molekül: schwere Ketten (rot), leichte Ketten (gelb). Antikörper (Immunglobuline, im internationalen Sprachgebrauch auch Immunoglobulin) sind Proteine (Eiweiße) aus der Klasse der Globuline, die in Wirbeltieren als Reaktion auf… …   Deutsch Wikipedia

  • variable region — noun also variable domain : the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free amino group −NH2, that varies greatly in its sequence of amino acid residues from one antibody to another, and that prob.… …   Useful english dictionary

  • Variable surface glycoprotein — Das Variable Surface Glycoprotein (Glykoprotein mit veränderlicher Oberfläche) wird von Trypanosomen gebildet, um die Immunantwort des Wirts zu unterlaufen. Es handelt sich um einen sehr effektiven Anpassungsmechanismus des Erregers an die… …   Deutsch Wikipedia

  • variable region — (VL and VH) The region at the N terminal end of immunoglobulin heavy and light chains whose amino acid sequence varies between antibodies of different specificity. Variable regions form the antigen binding site …   Dictionary of microbiology

  • variable region — Immunol. a configuration in the upper branches of the Y of an antibody molecule, unique in each antibody type, that binds with the determinant of a specific antigen. * * * …   Universalium

  • variable region —    A region in an immunoglobin molecule that shows many sequence differences between antibodies of different specificities; the part of the antibody that binds to the antigen …   Forensic science glossary

  • variable domain — Regions of antibody molecules that have different amino acid sequences in different antibody molecules. These regions are responsible for the antigen binding specificity of the antibody …   Glossary of Biotechnology

  • Human leukocyte antigen — The human leukocyte antigen system (HLA) is the name of the major histocompatibility complex (MHC) in humans. The superlocus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6 …   Wikipedia

  • Chimeric antigen receptor — Artificial T cell receptors (also known as chimeric T cell receptors, chimeric immunoreceptors, chimeric antigen receptors (CARs)) are engineered receptors, which graft an arbitrary specificity onto an immune effector cell. Typically, these… …   Wikipedia

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