(= transfer RNA; s-RNA; 4S RNA)The low molecular weight RNAs that specifically bind amino acids by amino-acylation to form aminoacyl tRNA, and that possess a special nucleotide triplet, the anticodon, sometimes containing the base inosine. They recognize codons on mRNA. By this recognition the appropriate tRNAs are brought into alignment in turn in the ribosome during protein synthesis (translation), there being at least one species of tRNA for each amino acid. In practice most cells possess about 30 types of tRNA. The amino acids are bound at the 3\' terminus that is always 3\'-ACC. The anticodon is around 34-38 nucleotides from the 5\' end and the total length of the various tRNAs is 70-80 bases.
Dictionary of molecular biology. 2004.