axin
A negative regulator of the Wnt signalling pathway. Binds to APC (adenomatous polyposis coli protein) and to b -catenin and regulates the stability of the catenin. Interacts directly with glycogen synthase kinase-3 (GSK-3) and promotes GSK-3 phosphorylation of b -catenin, which is then degraded.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Axin — 1 Masse/Länge Primärstruktur 862 Aminosäuren …   Deutsch Wikipedia

  • axin — Chem. (ˈæksɪn) An oleaginous and waxy product, yielded by the large Mexican cochineal (Coccus axinus), and used as a soothing ointment. aˈxinic a., of axin, as in the fatty axinic acid. Watts Fownes Chem. 698 …   Useful english dictionary

  • Axīn — Axīn, s. Age …   Meyers Großes Konversations-Lexikon

  • Axin — Axin, s. Age …   Lexikon der gesamten Technik

  • axın — is. 1. Sürətlə axan su; sel; iti cərəyan, güclü axan su, selab. Yağışdan əmələ gələn axın yolları xarab etdi. // Cərəyan, suyun axıb getdiyi tərəf. Çayın axını ilə üzmək. – Sən ki son nəfəsinlə vətəni andın; Çayların axını dayandı bir an. S. V..… …   Azərbaycan dilinin izahlı lüğəti

  • axin — (entrée créée par le supplément) (a ksin) s. m. Produit graisseux et cireux employé comme onguent contre les douleurs, au Mexique ; il est produit par la cochenille du jatropha curcas appelée coccus axinus …   Dictionnaire de la Langue Française d'Émile Littré

  • AXIN1 — Axin 1, also known as AXIN1, is a human gene. PBB Summary section title = summary text = This gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded… …   Wikipedia

  • AXIN2 — Axin 2 (conductin, axil), also known as AXIN2, is a human gene.cite web | title = Entrez Gene: AXIN2 axin 2 (conductin, axil)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=8313| accessdate = ] PBB Summary …   Wikipedia

  • Wnt signaling pathway — The Wnt signaling pathway describes a complex network of proteins most well known for their roles in embryogenesis and cancer, but also involved in normal physiological processes in adult animals.cite journal | author = Lie DC, Colamarino SA,… …   Wikipedia

  • DVL1 — Dishevelled, dsh homolog 1 (Drosophila) PDB rendering based on 1fsh …   Wikipedia

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