transcription factor


transcription factor
Protein required for recognition by RNA polymerases of specific stimulatory sequences in eukaryotic genes. Several are known that activate transcription by RNA polymerase II when bound to upstream promoters. Transcription of the 5S RNA gene in Xenopus by RNA polymerase III is dependent on a 40 kD protein TFIIIA that binds to a regulatory site in the centre of the gene, and was the first protein found to exhibit the metal-binding domains known as zinc fingers.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Transcription Factor II B — (TFIIB) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ |… …   Wikipedia

  • Transcription Factor II D — (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ |… …   Wikipedia

  • transcription factor — n any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription * * * a protein that regulates gene expression by binding to a DNA sequence adjacent to a sequence encoding a protein or… …   Medical dictionary

  • Transcription factor — In the field of molecular biology, a transcription factor (sometimes called a sequence specific DNA binding factor) is a protein that binds to specific sequences of DNA and thereby controls the transfer (or transcription) of genetic information… …   Wikipedia

  • Transcription Factor II F — protein Name = general transcription factor IIF, polypeptide 1, 74kDa caption = width = HGNCid = 4652 Symbol = GTF2F1 AltSymbols = TFIIF, BTF4, RAP74 EntrezGene = 2962 OMIM = 189968 RefSeq = NM 002096 UniProt = P35269 PDB = ECnumber = Chromosome …   Wikipedia

  • Transcription Factor II A — protein Name = general transcription factor IIA, 1, 19/37kDa caption = width = HGNCid = 4646 Symbol = GTF2A1 AltSymbols = EntrezGene = 2957 OMIM = 600520 RefSeq = NM 201595 UniProt = P52655 PDB = ECnumber = Chromosome = 14 Arm = q Band = 31… …   Wikipedia

  • Transcription Factor II E — protein Name = general transcription factor IIE, polypeptide 1, alpha 56kDa caption = width = HGNCid = 4650 Symbol = GTF2E1 AltSymbols = TF2E1 EntrezGene = 2960 OMIM = 189962 RefSeq = NM 005513 UniProt = P29083 PDB = ECnumber = Chromosome = 3 Arm …   Wikipedia

  • transcription factor — ▪ biology       molecule that controls the activity of a gene by determining whether the gene s DNA (deoxyribonucleic acid) is transcribed into RNA (ribonucleic acid). The enzyme RNA polymerase catalyzes the chemical reactions that synthesize RNA …   Universalium

  • Transcription Factor II H — protein Name= general transcription factor IIH, polypeptide 1, 62kDa caption= width= HGNCid=4655 Symbol=GTF2H1 AltSymbols= BTF2 EntrezGene=2965 OMIM=189972 RefSeq=NM 005316 UniProt=P32780 PDB= ECnumber= Chromosome=11 Arm=p Band=15.1… …   Wikipedia

  • transcription factor — noun Date: 1972 any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription …   New Collegiate Dictionary


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