thrombopoietin


thrombopoietin
Growth factor (19D) that regulates the proliferation of megakaryocytes and production of platelets (thrombopoiesis). Receptor is c-mpl, a cytokine receptor that can cause phosphorylation of STAT3 and STAT5 through Jak3.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Thrombopoietin — (leukemia virus oncogene ligand, megakaryocyte growth and development factor), also known as THPO, is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates… …   Wikipedia

  • thrombopoietin — thrombopoietin. См. тромбопоэтин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Thrombopoietin — Thrombopoetin oder auch Thrombopoietin (Abk. TPO) ist ein Hormon, das die Bildung und Differenzierung der Blutplättchen bildenden Zellen, der Megakaryozyten, stimuliert. Es ist im Rahmen der Thrombopoese notwendig für die Produktion von… …   Deutsch Wikipedia

  • thrombopoietin — /throm boh poy i tn, poy et n/, n. a hormone that induces bone marrow cells to form blood platelets. [1990 95; < Gk thrómbo(s) clot + poiet(és) maker; see IN2] * * * …   Universalium

  • thrombopoietin — noun A protein produced by the liver and kidney, which regulates the production of platelets …   Wiktionary

  • thrombopoietin — A cytokine that serves as a humoral regulator for the production of blood platelets through action on the receptor c mp1. SYN: megakaryocyte growth and development factor, megapoietin. [thrombo + G. poietes, maker, + in] * * * …   Medical dictionary

  • thrombopoietin — A colony stimulating factor that stimulates the production of blood cells, especially platelets, during chemotherapy. It is a cytokine that belongs to the family of drugs called hematopoietic (blood forming) agents …   English dictionary of cancer terms

  • thrombopoietin — /throm boh poy i tn, poy et n/, n. a hormone that induces bone marrow cells to form blood platelets. [1990 95; Gk thrómbo(s) clot + poiet(és) maker; see IN2] …   Useful english dictionary

  • Thrombopoietin receptor — Myeloproliferative leukemia virus oncogene Identifiers Symbols MPL; C MPL; CD110; MPLV; TPOR External IDs …   Wikipedia

  • Tpo — thrombopoietin …   Medical dictionary


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