thrombomodulin
Specific endothelial cell receptor (100 kD: luminal surface only) that forms a 1:1 complex with thrombin. This complex then converts protein C to Ca, that in turn acts on Factors Va and VIIIa. Structurally similar to coated pit receptors.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Thrombomodulin — Thrombomodulin, CD141 or BDCA 3 is an integral membrane protein expressed on the surface of endothelial cells.The protein has a molecular mass of 74kDa, and consists of a single chain with 5 distinct domains.It functions as a cofactor in the… …   Wikipedia

  • Thrombomodulin — Vorhandene Strukturdaten …   Deutsch Wikipedia

  • thrombomodulin — noun An antithrombotic membrane protein on the surface of endothelial cells …   Wiktionary

  • thrombomodulin — A glycoprotein present in the plasma membrane of endothelial cells that binds thrombin; participates in an additional regulatory mechanism in coagulation. [thrombo + odulate + in] * * * throm·bo·mod·u·lin (throm″bo modґu lin) an endothelial …   Medical dictionary

  • THBD — thrombomodulin …   Medical dictionary

  • THRM — thrombomodulin …   Medical dictionary

  • THBD — • thrombomodulin …   Dictionary of medical acronyms & abbreviations

  • THRM — • thrombomodulin …   Dictionary of medical acronyms & abbreviations

  • TBM — thrombomodulin; total body mass; Total Body Modification [TBM protocol]; tracheobronchiomegaly; trophoblastic basement membrane; tuberculous meningitis; tubular basement membrane …   Medical dictionary

  • TBM — • thrombomodulin; • total body mass; • Total Body Modification [TBM protocol]; • tracheobronchiomegaly; • trophoblastic basement membrane; • tuberculous meningitis; • tubular basement membrane …   Dictionary of medical acronyms & abbreviations

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