synaptobrevin
(= vSNARE; VAMP-2)
Small integral membrane proteins (16.7 kD) of synaptic vesicles. Two isoforms, VAMP-1 and VAMP-2 are known. Bind SNAPs and also interact with target-SNARE (syntaxin). Cleaved by clostridial toxins encoding zinc endopeptidases, such as tetanus toxin and botulinum toxin, blocking synaptic release.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Synaptobrevin — 1 3 verschiedene Ansichten der Struktur eines abgekürzten neuronalen SNARE Komplexes. Legende: Synaptobre …   Deutsch Wikipedia

  • Synaptobrevin — Synaptobrevins ( synaptobrevin isotypes 1 2 ) are small integral membrane proteins of secretory vesicles with molecular weight of 18 kilodalton (kDa) that are part of the vesicle associated membrane protein (VAMP) family.cite journal author =… …   Wikipedia

  • Synaptobrevin — [[Изображение:|px|Синаптобревин chemical structure]] Синаптобревин 1 (vesicle associated membrane protein 1) Обозначения Symbol(s) VAMP1 VAMP 1 Entrez …   Википедия

  • synaptobrevin — noun A small integral membrane protein of secretory vesicles …   Wiktionary

  • synaptobrevin — syn·ap·to·brev·in (sə nap″to brevґin) a membrane protein associated with synaptic vesicles and playing a central role in exocytosis of neurons and docking and fusion of synaptic vesicles on plasma membranes …   Medical dictionary

  • SYB — synaptobrevin …   Medical dictionary

  • SYB — • synaptobrevin …   Dictionary of medical acronyms & abbreviations

  • SYBL1 — Synaptobrevin like 1, also known as SYBL1, is a human gene.cite web | title = Entrez Gene: SYBL1 synaptobrevin like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6845| accessdate = ] PBB Summary section …   Wikipedia

  • SNARE (protein) — Molecular machinery driving vesicle fusion in neuromediator release. The core SNARE complex is formed by four α helices contributed by synaptobrevin, syntaxin and SNAP 25, synaptotagmin serves as a calcium sensor and regulates intimately the… …   Wikipedia

  • VAMP2 — Vesicle associated membrane protein 2 (synaptobrevin 2), also known as VAMP2, is a human gene.cite web | title = Entrez Gene: VAMP2 vesicle associated membrane protein 2 (synaptobrevin 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

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