streptozotocin
Methyl nitroso-urea with a 2-substituted glucose, used as an antibiotic (effective against growing Gram positive and Gram negative organisms), and also to induce a form of diabetes in experimental animals (rapidly induces pancreatic B cell necrosis if given in high dose). By using multiple low doses in a particular strain of mice, it is possible to produce insulitis followed later by diabetes, a model for juvenile-onset diabetes in humans.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Streptozotocin — (Streptozocin, STZ, Zanosar) is a naturally occurring chemical that is particularly toxic to the insulin producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in… …   Wikipedia

  • Streptozotocin — Strukturformel Allgemeines Freiname Streptozocin Andere Na …   Deutsch Wikipedia

  • streptozotocin — strep·to·zot·o·cin (strĕp tə zŏtʹə sĭn) n. An antibiotic, C8H15N3O7, produced by an actinomycete (Streptomyces achromogenes) and active against tumors but damaging to insulin producing cells and now also regarded as a carcinogen.   [strepto + zoo …   Universalium

  • streptozotocin — noun A naturally occurring chemical that is particularly toxic to the insulin producing beta cells of the pancreas in mammals, used to treat certain cancers …   Wiktionary

  • streptozotocin — SYN: streptozocin. * * * strep·to·zot·o·cin .strep tə zät ə sən n a broad spectrum antibiotic C8H15N3O7 with antineoplastic and diabetogenic properties that has been isolated from a bacterium of the genus Streptomyces (S. achromogenes) * * *… …   Medical dictionary

  • streptozotocin — strep·to·zot·o·cin …   English syllables

  • streptozotocin — ¦streptəˈzätəsə̇n noun ( s) Etymology: New Latin strepto (from Streptomyces achromogenes, bacterium from which it is produced) + English zotocin (perhaps from zo + toxic + mycin) : a broad spectrum antibiotic C8H15N3O7 with antineoplastic and… …   Useful english dictionary

  • Стрептозотоцин — вещество, токсичное для бета клеток поджелудочной железы. По структуре достаточно напоминает молекулы сахара, чтобы захватываться и транспортироват …   Википедия

  • STZ — Streptozotocin (Medical » Laboratory) * Constellation Brands Inc. (Business » NYSE Symbols) * Set Zero (Computing » Assembly) * Signal Technology Corporation (Business » AMEX Symbols) * Santa Terezinha, MT, Brazil (Regional » Airport Codes) *… …   Abbreviations dictionary

  • Streptozocin — Strukturformel Allgemeines Freiname Streptozocin …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”