SNAREs


SNAREs
Receptors for SNAPs. The neuronal receptor for vesicle-SNAPs, v-SNARE, is synaptobrevin, also known as VAMP-2. The target (t-SNARE) associated with the plasma membrane of the axonal terminal is syntaxin. The SNAP-SNARE complex is apparently responsible for regulating vesicle targeting: neurotoxins such as tetanus toxin and botulinum toxin selectively cleave SNAREs or SNAPs. See also cellubrevin.

Dictionary of molecular biology. 2004.

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