signal recognition particle-receptor
Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also known as docking protein. Heterodimeric, both protomers having GTP-binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message, and nascent polypeptide chain binds to the SRP-receptor is the block to further chain elongation released - and concurrently the SRP is released, leaving the ribosome attached to the ER membrane. Co-translational transport of the polypeptide delivers it into the lumen of the ER.

Dictionary of molecular biology. 2004.

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  • Signal recognition particle receptor — Pfam box Symbol = SRX Name = SRX width = caption = Pfam= PF09201 InterPro= IPR015284 SMART= Prosite = SCOP = 1nrj TCDB = OPM family= 145 OPM protein= 1nrj PDB=PDB3|1nrjA:1 155Signal recognition particle (SRP) receptor also called docking protein …   Wikipedia

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  • docking protein — See signal recognition particle receptor …   Dictionary of molecular biology

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