The carbohydrate moiety of many vertebrate glycoproteins bears terminal residues of sialic acid. If such residues are removed, eg. by treatment with a neuraminidase, the resulting proteins are known as asialoglycoproteins. In the case of certain plasma proteins, the asialo-derivatives are specifically bound by a receptor on the surface of liver parenchymal cells (the scavenger receptor).
Dictionary of molecular biology. 2004.