receptor tyrosine kinase
Class of membrane receptors that phosphorylate tyrosine residues. Many play significant roles in development or cell division. Examples: insulin receptor family, c- ros receptor, Drosophila sevenless, trk family.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Receptor tyrosine kinase — Receptor tyrosine kinases (RTK)s are the high affinity cell surface receptors for many polypeptide growth factors, cytokines and hormones. Of the ninety unique tyrosine kinase genes idenitified in the human genome, 58 encode receptor tyrosine… …   Wikipedia

  • AXL receptor tyrosine kinase — AXL receptor tyrosine kinase, also known as AXL, is a human gene.cite web | title = Entrez Gene: AXL AXL receptor tyrosine kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=558| accessdate = ] PBB… …   Wikipedia

  • Related to receptor tyrosine kinase — protein name=RYK receptor like tyrosine kinase caption= width= HGNCid=10481 Symbol=RYK AltSymbols=JTK5A EntrezGene=6259 OMIM=600524 RefSeq=NM 001005861 UniProt= PDB= ECnumber=2.7.1.112 Chromosome=3 Arm=q Band=22.1 LocusSupplementaryData=The… …   Wikipedia

  • Non-receptor tyrosine kinase — non membrane spanning protein tyrosine kinase Identifiers EC number 2.7.10.2 Databases IntEnz In …   Wikipedia

  • vascular endothelial growth factor receptor tyrosine kinase inhibitor — VEGFR tyrosine kinase inhibitor. A substance that blocks an enzyme needed to form blood vessels. Also called VEGFR tyrosine kinase inhibitor …   English dictionary of cancer terms

  • Tyrosine kinase 2 — Tyrosine kinase 2, also known as TYK2, is a human gene.cite web | title = Entrez Gene: TYK2 tyrosine kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7297| accessdate = ] Tyk2 was the first member… …   Wikipedia

  • Tyrosine kinase — A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a tyrosine residue in a protein. Tyrosine kinases are a subgroup of the larger class of protein kinases. Phosphorylation of proteins by kinases is an important… …   Wikipedia

  • receptor protein-tyrosine kinase — re·cep·tor pro·tein ty·ro·sine ki·nase (re sepґtər proґtēn tiґro sēn kiґnās) [EC 2.7.10.1] a group comprising those protein tyrosine kinases with a transmembrane domain and cytoplasmic tyrosine kinase activity. They are… …   Medical dictionary

  • tyrosine kinase — Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single… …   Dictionary of molecular biology

  • tyrosine kinase inhibitor — any one of a class of drugs that interfere with cell growth in a variety of different ways by inhibiting the action of tyrosine kinases. This family of enzymes, which occur both within cells and as components of cell membrane receptor sites, have …   The new mediacal dictionary

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