proteolipid protein
Highly conserved membrane protein (30 kD) in myelin. Cellular function obscure but mutations lethal eg. jimpy mouse and Pelizaeus-Merzbacher disease of man.

Dictionary of molecular biology. 2004.

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  • Proteolipid-Protein — Masse/Länge Primärstruktur 276 Aminosäuren …   Deutsch Wikipedia

  • proteolipid protein — (PLP) a hydrophobic protein that is the major constituent of myelin in the central nervous system. Defective synthesis of PLP results in Pelizaeus Merzbacher disease. Called also lipophilin …   Medical dictionary

  • Proteolipid protein 1 — is a protein associated with Pelizaeus Merzbacher disease. It is a 4 transmembrane domain protein which binds strongly to other copies of itself on the extracellular side of the membrane. In a myelin sheath, as the layers of myelin wraps come… …   Wikipedia

  • Proteolipid protein (PLP) — The most abundant protein of the myelin sheath (the covering of the nerves) in the central nervous system (CNS). The gene that codes for PLP is on the X chromosome. Mutations in PLP cause Pelizaeus Merzbacher disease (PMD), an X linked recessive… …   Medical dictionary

  • Myelin proteolipid protein — (PLP or lipophilin) Identifiers Symbol Myelin PLP Pfam PF01275 InterPro …   Wikipedia

  • PLP (proteolipid protein) — The most abundant protein of the myelin sheath (the covering of the nerves) in the central nervous system (CNS). The gene that codes for PLP is on the X chromosome. Mutations in PLP cause Pelizaeus Merzbacher disease (PMD), an X linked recessive… …   Medical dictionary

  • Protein, proteolipid (PLP) — The most abundant protein of the myelin sheath (the covering of the nerves) in the central nervous system (CNS). The gene that codes for PLP is on the X chromosome. Mutations in PLP cause Pelizaeus Merzbacher disease (PMD), an X linked recessive… …   Medical dictionary

  • proteolipid — pro·teo·lip·id lip əd also pro·teo·lip·ide lip .īd n any of a class of proteins that contain a considerable percentage of lipid and are soluble in lipids and insoluble in water * * * pro·teo·lip·id (pro″te o lipґid) 1. a conjugated protein… …   Medical dictionary

  • Myelin basic protein — Rendering of MBP from PDB 1BX2 …   Wikipedia

  • Myelin basic protein — Das Myelin Basische Protein abgek. MBP, engl.: myelin basic protein ist ein Protein, das eine große Bedeutung für die Myelinscheide der Nervenzellen besitzt. Im Proteinanteil des Myelins macht es etwa 40 Prozent aus. In der Forschung über die… …   Deutsch Wikipedia

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