proline
(= pro; P; 115D)
One of the 20 amino acids directly coded for in proteins. Structure differs from all the others, in that its side chain is bonded to the nitrogen of the a -amino group, as well as the a -carbon. This makes the amino group a secondary amine, and so proline is described as an imino acid. Has strong influence on secondary structure of proteins and is much more abundant in collagens than in other proteins, occurring especially in the sequence glycine-proline hydroxyproline. A proline-rich region seems to characterize the binding site of SH3 domains.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Proline — L ou S( ) proline   et   D ou R(+) proline …   Wikipédia en Français

  • proline — ● proline nom féminin Acide aminé non essentiel (qui peut être synthétisé par l organisme), présent en abondance dans les protéines. proline [pʀɔlin] n. f. ÉTYM. 1905, → cit.; all. Prolin dû à Fischer et Abderhalden, 1901. → cit. ❖ ♦ Chim., biol …   Encyclopédie Universelle

  • proline — [prō′lēn΄, prō′lin] n. [Ger prolin, contr. < pyrrolidin < pyrrol, PYRROLE + id, IDE + in, INE3] a nonessential amino acid, C4H8N COOH, formed by the decomposition of proteins: see AMINO ACID …   English World dictionary

  • Proline — For other uses, see Proline (disambiguation). Proline …   Wikipedia

  • proline — /proh leen, lin/, n. Biochem. an alcohol soluble amino acid, C4H9NHCOOH, occurring in high concentration in collagen. Abbr.: Pro; Symbol: P [1900 05; alter. of PYRROLIDINE] * * * One of the nonessential amino acids, found in many proteins,… …   Universalium

  • proline — Pyrrolidine 2 carboxylic acid; the l isomer is found in proteins, especially the collagens. SYN: pyrrolidine 2 carboxylate. p. aminopeptidase SYN: p. iminopeptidase. p. dehydrogenase SYN: pyrroline 2 carboxylate reductase, pyrroline 5 carboxylate …   Medical dictionary

  • proline — prolinas statusas T sritis chemija formulė NC₄H₈COOH santrumpa( os) Pro, P atitikmenys: angl. proline rus. пролин ryšiai: sinonimas – 2 pirolidinkarboksirūgštis …   Chemijos terminų aiškinamasis žodynas

  • proline — noun Etymology: German Prolin, contraction of Pyrrolidin pyrrolidine (C4H9N), from International Scientific Vocabulary pyrrole + idine Date: 1904 an amino acid C5H9NO2 that can be synthesized by animals from glutamate …   New Collegiate Dictionary

  • proline — noun A nonessential amino acid CHNO found in most animal proteins, especially collagen; its cyclic structure leads to kinks in the peptide chain of proteins. Syn: Pro …   Wiktionary

  • proline — n. amino acid found in collagen …   English contemporary dictionary

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