(= peroxisome proliferator-activated receptors)
PPAR a stimulates b -oxidative degradation of fatty acids, PPAR g promotes lipid storage by regulating adipocyte differentiation. Are implicated in metabolic disorders predisposing to atherosclerosis and inflammation. PPAR a -deficient mice show prolonged response to inflammatory stimuli. PPAR a is activated by gemfibrozil and other fibrate drugs.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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