PPAR
(= peroxisome proliferator-activated receptors)
PPAR a stimulates b -oxidative degradation of fatty acids, PPAR g promotes lipid storage by regulating adipocyte differentiation. Are implicated in metabolic disorders predisposing to atherosclerosis and inflammation. PPAR a -deficient mice show prolonged response to inflammatory stimuli. PPAR a is activated by gemfibrozil and other fibrate drugs.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • PPAR — • peroxisome proliferator activated receptor …   Dictionary of medical acronyms & abbreviations

  • PPAR modulator — PPAR modulators are drugs which act upon the peroxisome proliferator activated receptor.ClassificationPPARα and PPARγ are the molecular targets of a number of marketed drugs. The three main classes of PPAR drugs are:PPAR alpha modulatorsPPAR… …   Wikipedia

  • Peroxisome proliferator-activated receptor gamma — PDB rendering based on 1fm6 …   Wikipedia

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