plaque assay
(1) Assay for virus in which a dilute solution of the virus is applied to a culture dish containing a layer of the host cells; convective spread is prevented by making the medium very viscous. After incubation the ‘plaques’, areas in which cells have been killed (or transformed), can be recognized, and the number of infective virus particles in the original suspension estimated.
(2) Assay for cells producing antibody against erythrocytes or against antigen that has been bound to the erythrocytes. The cell is surrounded by a clear plaque of haemolysis. Basic principle behind the assay is the same as for the virus plaque assay.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • Assay — Das Wort Assay (deutsch: Test, Probe) stammt aus dem englischen Sprachraum und bedeutet dort allgemein eine Untersuchung zum Nachweis bestimmter Substanzen (z. B. Metalle). In der deutschen Sprache bezeichnet Assay vor allem in der… …   Deutsch Wikipedia

  • plaque-forming cell — Antibody secreting cell detected in a plaque assay …   Dictionary of molecular biology

  • Assay — An assay is an analysis done to determine: {{}}The presence of a substance and the amount of that substance. Thus, an assay may be done for example to determine the level of thyroid hormones in the blood of a person suspected of being hypothyroid …   Medical dictionary

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