phosphatidyl choline
The major phospholipid of most mammalian cell membranes where the 1-acyl residue is normally saturated and the 2-acyl residue unsaturated. Choline is attached to phosphatidic acid by a phosphodiester linkage. Major synthetic route is from diacyl glycerol and CDP-choline. Forms monolayers at an air/water interface, and forms bilayer structures (liposomes) if dispersed in aqueous medium. A zwitterion over a wide pH range. Readily hydrolyzed in dilute alkali.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • choline — Esterified in the head group of phospholipids (phosphatidyl choline and sphingomyelin) and in the neurotransmitter acetylcholine. Otherwise a biological source of methyl groups …   Dictionary of molecular biology

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  • Lecithin — is any of a group of yellow brownish fatty substances occurring in animal and plant tissues, and in egg yolk, composed of phosphoric acid, choline, fatty acids, glycerol, glycolipids, triglycerides, and phospholipids (e.g., phosphatidylcholine,… …   Wikipedia

  • lecithin — /les euh thin/, n. 1. Biochem. any of a group of phospholipids, occurring in animal and plant tissues and egg yolk, composed of units of choline, phosphoric acid, fatty acids, and glycerol. 2. a commercial form of this substance, obtained chiefly …   Universalium

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  • Membrane curvature — is the geometrical measure or characterization of the curvature of membranes. The membranes can be naturally occurring or man made (synthetic). An example of naturally occurring membrane is the lipid bilayer of cells, also known as cellular… …   Wikipedia

  • sphingomyelin — A sphingolipid in which the head group is phosphoryl choline. A close analogue of phosphatidyl choline. In many cells the concentration of sphingomyelin and phosphatidyl choline in the plasma membrane seems to bear a reciprocal relationship …   Dictionary of molecular biology

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