peptide nucleic acid
Synthetic nucleic acid mimic, in which the sugar-phosphate backbone is replaced by a peptide-like polyamide. Instead of 5&’ and 3&’ ends, PNAs have N and C termini. Their resistance to both nucleases and proteinases, and their ability to bind closely to complementary DNA or RNA sequences, have made them promising candidates in antisense and gene therapy technologies.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Peptide nucleic acid — (PNA) is an artificially synthesized polymer similar to DNA or RNA and is used in biological research and medical treatments. PNA is not known to occur naturally.DNA and RNA have a deoxyribose and ribose sugar backbone, respectively, whereas PNA… …   Wikipedia

  • peptide nucleic acid — noun A compound analogous to DNA in which a synthetic peptide takes the place of the sugar in DNA • • • Main Entry: ↑pepsin …   Useful english dictionary

  • Peptide Nucleic Acid — Acide nucléique peptidique Pour les articles homonymes, voir ANP et PNA. L acide nucléique peptidique (ANP) ou Peptide Nucleic Acid, (PNA) en anglais, est une molécule aux bases similaires à l ADN ou à l ARN mais qui se différencie par son… …   Wikipédia en Français

  • Peptide nucleic acid — Acide nucléique peptidique Pour les articles homonymes, voir ANP et PNA. L acide nucléique peptidique (ANP) ou Peptide Nucleic Acid, (PNA) en anglais, est une molécule aux bases similaires à l ADN ou à l ARN mais qui se différencie par son… …   Wikipédia en Français

  • peptide nucleic acid — Abbreviation: PNA A synthetic oligonucleotide analogue, in which the sugar backbone is replaced by a peptide chain, upon which the nucleoside residues are strung. Probes made from PNA appear to have greater specificity than those made from DNA …   Glossary of Biotechnology

  • Peptide nucleic acid — …   Википедия

  • Nucleic acid — Nucleic acids are biological molecules essential for life, and include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Together with proteins, nucleic acids make up the most important macromolecules; each is found in abundance in all… …   Wikipedia

  • Nucleic acid analogues — Not to be confused with degenerate bases. For phosphoramidite synthesis of nucleic acids, see Oligonucleotide synthesis. RNA with its nucleobases to the left and DNA to the right. Nucleic acid analogues are compounds structurally similar (analog) …   Wikipedia

  • Nucleic acid templated chemistry — The schematic presentation how the nucleic acid templated chemistry works within cells Schemati …   Wikipedia

  • Threose nucleic acid — (TNA) is a polymer similar to DNA or RNA but differing in the composition of its backbone . TNA is not known to occur in existing life on Earth.DNA and RNA have a deoxyribose and ribose sugar backbone, respectively, whereas TNA s backbone is… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”