orotic acid


orotic acid
(= orotate)
Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5\'-phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5\'-phosphate).

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Orotic acid — Systematic (IUPAC) name 1,2,3,6 tetrahydro 2,6 dioxo 4 pyrimidinecarboxylic acid Clinical data AHFS/Drugs.com …   Wikipedia

  • orotic acid — orotic acid. См. оротовая кислота. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • orotic acid — oroto rūgštis statusas T sritis chemija formulė (HO)₂C₄HN₂COOH santrumpa( os) Oro atitikmenys: angl. orotic acid; vitamin B₁₃ rus. витамин B₁₃; оротовая кислота ryšiai: sinonimas – 2,6 dihidroksi 4 pirimidinkarboksirūgštis sinonimas – vitaminas… …   Chemijos terminų aiškinamasis žodynas

  • orotic acid — (ˈ)ȯ|räd.ik noun Etymology: orotic probably from orot (from Greek oros whey) + icmore at serum : a crystalline acid C4H4N2O4 that was first found in milk, is a growth factor for various microorganisms (as Lactobacillus bulgaricus), and is a… …   Useful english dictionary

  • orotic acid — 6 Carboxyuracil; uracil 6 carboxylic acid; an important intermediate in the formation of the pyrimidine nucleotides; elevated in certain inherited defects of pyrimidine biosynthesis. SYN: uracil 6 carboxylic acid. * * * orot·ic acid ȯr .ät ik n …   Medical dictionary

  • orotic acid — noun pyrimidine carboxylic acid …   Wiktionary

  • Orotic aciduria — Classification and external resources orotic acid ICD 9 281 …   Wikipedia

  • orotic aciduria — A rare disorder of pyrimidine metabolism characterized by hypochromic anemia with megaloblastic changes in bone marrow, leukopenia, retarded growth, and urinary excretion of orotic acid; …   Medical dictionary

  • orotic — adjective Of or pertaining to orotic acid or its derivatives …   Wiktionary

  • 4,5-Dihydroorotic acid — IUPAC name 2,6 dioxo 1,3 diazinane 4 carboxylic acid …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.