nitrogen mustards
A series of tertiary amine compounds having vesicant properties similar to those of mustard gas. They have the general formula RN(CH2CH2Cl) 2. They can alkylate compounds such as DNA and are used as the basis of cytostatic drugs for cancer chemotherapy.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Nitrogen mustard — HN1 (bis(2 chloroethyl)ethylamine) …   Wikipedia

  • HN3 (nitrogen mustard) — Tris(2 chloroethyl)amine …   Wikipedia

  • Sulfur mustard — Sulfur mustard …   Wikipedia

  • Tris(2-chloroethyl)amine — Chembox new Name = Tris(2 chloroethyl)amine ImageFile = Nitrogen mustard HN3.png ImageName = Tris(2 chloroethyl)amine ImageFile1 = HN3 3D vdW.png ImageName1 = Tris(2 chloroethyl)amine IUPACName = 2 chloro N,N bis(2 chloroethyl)ethanamine… …   Wikipedia

  • Mechlorethamine — Systematic (IUPAC) name 2 chloro N (2 chloroethyl) N methyl ethanamine Clinical data AHFS/ …   Wikipedia

  • heterocyclic compound — Any of a class of organic compounds whose molecules contain one or more rings of atoms with at least one atom (the heteroatom) being an element other than carbon, most frequently oxygen, nitrogen, or sulfur. As in regular cyclic hydrocarbons,… …   Universalium

  • Cyclophosphamide — Systematic (IUPAC) name …   Wikipedia

  • Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… …   Wikipedia

  • Melphalan — Systematic (IUPAC) name 4 [bis(chloroethyl)amino]phenylalanine Clinical data Trade names Alkeran …   Wikipedia

  • Bis(2-chloroethyl)ethylamine — Chembox new Name = Bis(2 chloroethyl)ethylamine ImageFile = Nitrogen mustard HN1.png ImageName = HN1 IUPACName = 2 chloro N (2 chloroethyl) N ethyl ethanamine; Compound 4644; ethyl bis( 2 chloroethyl)amine; Bis (2 chloroethyl)amine; HN1 Section1 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”