myeloperoxidase
A metallo-enzyme containing iron, found in the lysosomal granules of myeloid cells, particularly macrophages and neutrophils; responsible for generating potent bacteriocidal activity by the hydrolysis of hydrogen peroxide (produced in the metabolic burst) in the presence of halide ions. Deficiency of myeloperoxidase is not fatal, and it is reportedly absent entirely in chickens.

Dictionary of molecular biology. 2004.

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  • Myeloperoxidase — drawn from PDB 1D7W …   Wikipedia

  • Myeloperoxidase — Vorhandene Strukturdaten: s. UniProt Masse/Länge …   Deutsch Wikipedia

  • Myeloperoxidase — Myéloperoxidase La myéloperoxidase est une enzyme halogénodependante active contre E. coli et L. acidophilus pour des pH acides (= 5). L ajout de peroxyde n est pas nécessaire pour Lactobacillus puisque ce dernier le produit lui même. L halogène… …   Wikipédia en Français

  • Myéloperoxidase — La myéloperoxidase est une enzyme halogénodependante active contre E. coli et L. acidophilus pour des pH acides (= 5). L ajout de peroxyde n est pas nécessaire pour Lactobacillus puisque ce dernier le produit lui même. L halogène le plus efficace …   Wikipédia en Français

  • myeloperoxidase — noun A peroxidase enzyme most abundantly present in neutrophil granulocytes, responsible for the greenish colour of pus and mucus …   Wiktionary

  • myeloperoxidase — A peroxidase occurring in phagocytic cells that can oxidize halogen ions ( e.g., I−) to the free halogen; an autosomal recessive deficiency of m. leads to impaired bacterial killing. * * * my·e·lo·per·ox·i·dase .mī ə lō pə räk sə .dās, .dāz …   Medical dictionary

  • myeloperoxidase — my·elo·peroxidase …   English syllables

  • myeloperoxidase — ˌ noun Etymology: myel + peroxidase : a peroxidase of phagocytic cells (as neutrophils and monocytes) that is held to assist in bactericidal activity by catalyzing the oxidation of ionic halogen to free halogen …   Useful english dictionary

  • Myeloperoxidase deficiency — Classification and external resources Hypochlorous acid is normally produced by myeloperoxidase OMIM …   Wikipedia

  • myeloperoxidase (MPO) deficiency — my·elo·per·ox·i·dase (MPO) de·fi·cien·cy (mi″ə lo pər okґsĭ dās) an autosomal recessive disorder caused by mutation in the myeloperoxidase gene (MPO, locus:17q23.1), characterized by the complete absence of MPO in… …   Medical dictionary

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