mitomycin C


mitomycin C
Aziridine antibiotic isolated from Streptomyces caespitosus. Inhibits DNA synthesis by cross-linking the strands and is used as an anti-neoplastic agent. Most active in late G1 and early S phase. Mitomycin-treated cells are sometimes used as feeder layers.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Mitomycin — Preferred IUPAC name [6 Amino 8a methoxy 5 methyl 4,7 dioxo 1,1a,2,4,7,8,8a,8b octahydroazireno[2 ,3 :3,4]pyrrolo[1,2 a]indol 8 yl]me …   Wikipedia

  • Mitomycin — Strukturformel Allgemeines Freiname Mitomycin Andere Namen …   Deutsch Wikipedia

  • mitomycin — Antibiotic produced by Streptomyces caespitosus, variants of which are designated m. A, m. B, etc.; m. C is an antineoplastic agent and a bacteriocide; inhibits DNA synthesis. * * * mi·to·my·cin .mīt ə mīs ən n 1) a complex of antibiotic… …   Medical dictionary

  • mitomycin — an anthracycline antibiotic that inhibits the growth of cancer cells. Administered by injection or bladder instillation, it causes severe marrow suppression but is of use in the treatment of stomach, breast, and bladder cancers. Trade names:… …   The new mediacal dictionary

  • mitomycin — noun Etymology: International Scientific Vocabulary mito (probably from New Latin mitosis) + mycin Date: 1956 a complex of antibiotic substances that is produced by a Japanese streptomyces (Streptomyces caespitosus); especially one form… …   New Collegiate Dictionary

  • mitomycin — mi·to·my·cin (mī tə mīʹsĭn) n. Any of a group of antibiotics produced by the soil actinomycete Streptomyces caespitosus that inhibit DNA synthesis and are used against bacteria and cancerous tumor cells.   [Probably mitosis + mycin.] * * * …   Universalium

  • mitomycin — noun Any of a family of aziridine containing natural products isolated from the filamentous bacterium Streptomyces lavendulae, one of which is used as a chemotherapeutic agent …   Wiktionary

  • Mitomycin — Mi|to|my|cin [... tsi:n] u. Mi|to|my|zin das; s, e Kurzw. aus ↑Mitoseu. ↑Streptomycin> (vor allem in der Krebstherapie angewendetes) ↑zytostatischwirksames ↑Antibiotikum …   Das große Fremdwörterbuch

  • mitomycin — mi·to·my·cin …   English syllables

  • mitomycin — An anticancer drug that belongs to the family of drugs called antitumor antibiotics …   English dictionary of cancer terms


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.