mismatch repair
A DNA repair system that detects and replaces wrongly paired, mismatched, bases in newly replicated DNA. E. coli has a mismatch correction enzyme coded for by three genes mutH, mutL and mutS, that is directed to the newly synthesized strand and removes a segment of that strand including the incorrect nucleotide. The gap is then filled by DNA polymerase.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Mismatch repair — Pour les articles homonymes, voir mismatch. En biologie moléculaire, le mismatch repair désigne le système de reconnaissance et de réparation des mésappariements de l ADN. Ce mécanisme s est conservé au cours de l évolution, si bien qu il est… …   Wikipédia en Français

  • Mismatch repair — A system within the cell for correcting errors in DNA that works by detecting and replacing bases in the DNA that are wrongly paired (mismatched bases). The system repairs the mismatch. When there is a mismatch in the DNA, a mismatch correction… …   Medical dictionary

  • mismatch repair — A DNA repair process that corrects mismatched base pairs …   Glossary of Biotechnology

  • Mismatch repair cancer syndrome — Classification and external resources OMIM 276300 DiseasesDB 29793 eMedicine …   Wikipedia

  • mismatch repair gene — any of various genes involved in mismatch repair of DNA, correcting errors introduced during replication; defects lead to slow accumulation of errors and increased frequency of recombination and mutation, and are associated with microsatellite… …   Medical dictionary

  • DNA mismatch repair — is a system for recognizing and repairing erroneous insertion, deletion and mis incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.[1][2] Mismatch repair is strand… …   Wikipedia

  • Mismatch — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Le terme mismatch (de l anglais mis, mal et match, adapté) désigne ce qui n est pas ou plus adapté. En sciences Mismatch en psychologie évolutionniste… …   Wikipédia en Français

  • Repair, mismatch — A system within the cell for correcting errors in DNA that works by detecting and replacing bases in the DNA that are wrongly paired (mismatched bases). The system repairs the mismatch. When there is a mismatch in the DNA, a mismatch correction… …   Medical dictionary

  • repair — Restoration of diseased or damaged tissues naturally by healing processes or artificially, as by surgical means. [M.E., fr. O.Fr., fr. L. re paro, fr. re , back, again, + paro, prepare, put in order] chemical r. conversion of a free radical to a… …   Medical dictionary

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

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