angiotensin


angiotensin
A peptide hormone. Angiotensinogen (renin substrate) is a 60 kD polypeptide released from the liver and cleaved in the circulation by renin to form the biologically inactive decapeptide angiotensin I. This is in turn cleaved to form active angiotensin II by Angiotensin Converting Enzyme (ACE). Angiotensin II causes contraction of vascular smooth muscle, and thus raises blood pressure, and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Angiotensin — causes blood vessels to constrict, and drives blood pressure up. It is part of the renin angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also creates aldosterone, which causes the tubules of the… …   Wikipedia

  • Angiotensin II — Kalottenmodell nach PDB  …   Deutsch Wikipedia

  • Angiotensin I — Kugelmodell nach PDB  …   Deutsch Wikipedia

  • angiotensin — [an΄jē ō ten′sin] n. [ ANGIO + TENS(ION) + IN1] a polypeptide that is a powerful vasopressor, formed in the blood by the action of renin on a plasma protein …   English World dictionary

  • angiotensin — /an jee oh ten sin/, n. Biochem. any of three oligopeptides occurring in plasma, an inactive form (angiotensin I) and two varieties (angiotensin II and angiotensin III) that elevate blood pressure and stimulate the adrenal cortex to secrete… …   Universalium

  • Angiotensin — An|gio|ten|sin 〈n. 11; Pharm.〉 Gewebshormon, das aus acht Aminosäuren besteht u. blutdrucksteigernd wirkt [<grch. aggeion „Gefäß“ + lat. tendere „spannen“] * * * An|gi|o|ten|sin [griech. aggeĩon = Gefäß u. lat. tendere, tensum = spannen; ↑ in …   Universal-Lexikon

  • Angiotensin — A family of peptides (smaller than proteins) that act as vasoconstrictors to narrow blood vessels. * * * A family of peptides of known and similar sequence, with vasoconstrictive activity, produced by enzymatic action of renin upon… …   Medical dictionary

  • Angiotensin — Kalottenmodelle der Angiotensine I und II. Angiotensine, früher Angiotonine oder Hypertensine, sind eine zu den Gewebshormonen zählende Gruppe von Peptidhormonen, die durch enzymatische Spaltung aus Angiotensinogen der Leber gebildet werden. Dazu …   Deutsch Wikipedia

  • angiotensin II — A vasoactive octapeptide produced by the action of angiotensin converting enzyme on angiotensin I; produces stimulation of vascular smooth muscle, promotes aldosterone production, and stimulates the sympathetic nervous …   Medical dictionary

  • angiotensin — n. either of two peptides: angiotensin I or angiotensin II. Angiotensin I is derived, by the action of the enzyme renin, from a protein (alpha globulin) secreted by the liver into the bloodstream. As blood passes through the lungs, another enzyme …   The new mediacal dictionary


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