metabolic cooperation


metabolic cooperation
Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids. Transfer is via channels constituted by the connexons of gap junctions, and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radiolabelled purines were transferred from wild-type cells to mutants unable to utilize exogenous purines.

Dictionary of molecular biology. 2004.

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