MCSF


MCSF
(= CSF-1; macrophage colony-stimulating factor)
A 40-76 kD glycoprotein that plays an important role in the activation and proliferation of microglial cells both in vitro and in injured neural tissue, is important in adipocyte hyperplasia, in osteoclast differentiation and in one of the early events in atherosclerosis, monocyte to macrophage differentiation in the arterial intima. The receptor for MCSF (c-fms) is expressed on the pluripotent precursor and mature osteoclasts and macrophages. Mutation in MCSF leads to osteopetrosis because of osteoclast deficiency.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

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  • autocode format — An abbreviated and formatted message header used in conjunction with the mobile cryptologic support facility (MCSF) to energize the automatic communications relay functions of the MCSF, providing rapid exchange of data through the system …   Military dictionary

  • CSF-1 — Saltar a navegación, búsqueda Macrophage colony stimulating factor (MCSF) o también Colony stimulating factor 1 (CSF 1), es una citoquina secretada que induce a las células madre hemopoiéticas a diferenciarse a macrófago o otros tipos celulares… …   Wikipedia Español


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