mannan-binding lectin

mannan-binding lectin
(= MBL; formerly mannan-binding protein, MBP)
Plasma protein (32 kD) structurally related to complement C1, that binds specific carbohydrates (mannans) on the surface of various microorganisms including bacteria, yeasts, parasitic protozoa, and viruses; activates the complement cascade through MASP and promotes phagocytosis. Deficiency is associated with frequent infections in childhood.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Mannan-binding lectin — Mannose binding lectin (protein C) 2, soluble PDB rendering based on 1hup …   Wikipedia

  • Mannan-binding lectin pathway — Natta projection of mannose in its α D mannopyranose form. Mannan is a polymer of mannose. The Mannan binding lectin pathway (also known simply as the Lectin Pathway) is similar in structure to the classical complement pathway,[1] …   Wikipedia

  • Mannan — For the god of the sea, see Manannan mac Lir. For the Tamil film, see Mannan (film). Mannan is a plant polysaccharide that is a polymer of the sugar mannose.[1] Detection of mannan leads to lysis in the mannan binding lectin pathway.It is… …   Wikipedia

  • lectin complement pathway — (lek tin) The lectin pathway for complement activation is triggered by the binding of a serum lectin (mannan binding lectin; MBL) to mannose containing proteins or to carbohydrates on viruses or bacteria …   Dictionary of microbiology

  • Mannose-binding protein-associated serine protease — are serine proteases involved in the complement system. Types include: MASP1 (protein) MASP2 (protein) See also mannan binding lectin …   Wikipedia

  • Carbohydrate-binding module — CBM 1 three dimensional structures of three engineered cellulose binding domains of cellobiohydrolase i from trichoderma reesei, nmr, 18 structures Identifiers Symbol CBM 1 …   Wikipedia

  • Map44 — mannan binding lectin serine peptidase 1 (C4/C2 activating component of Ra reactive factor) Identifiers Symbol MASP1 Alt. symbols CRARF, PRSS5 Entrez …   Wikipedia

  • Anti-saccharomyces cerevisiae antibodies — AbBox Antigen = saccharomyces cerevisiae OneIsoform = yes OneIsoformSpecialName = Mannins OneSource = Saccharomyces cerevisiae OneGene = OneOrgan = Large Intestine OneTissue = Epithelium OneCell = OneAlso = OneDisease = Colitis OneIgClass =… …   Wikipedia

  • Coronavirus Félin — Coronavirus …   Wikipédia en Français

  • Coronavirus felin — Coronavirus félin Coronavirus …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.